LmjF.17.0580

bis(5'-nucleosyl)-tetraphosphatase, symmetrical-like protein
Leishmania major strain Friedlin OG6: OG6_199786 OG7: OG7_0008422 28 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 28 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.01.0830 ⚠
metallo-peptidase, Clan MA(E), Family M3
— Both
LmjF.15.0510 ⚠
ecotin, putative
— OG7
LmjF.15.0300 ⚠
Ecotin-like protein
— OG7
LmjF.13.0680 ⚠
Metallopeptidase family M24, putative
— OG7
LmjF.35.0370 ⚠
ATP-dependent DEAD-box RNA helicase, putative
— OG7
LmjF.01.0770 ⚠
Eukaryotic initiation factor 4A-1
— OG7
LmjF.34.0150 ⚠
malate dehydrogenase, putative
— OG7
LmjF.28.1530 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LmjF.01.0780 ⚠
Eukaryotic initiation factor 4A-1
— OG7
LmjF.29.0300 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.0130 ⚠
malate dehydrogenase, putative
— OG7
LmjF.19.0710 ⚠
glycosomal malate dehydrogenase
— OG7
LmjF.36.4450 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LmjF.07.0190 ⚠
protein phosphatase 2A, regulatory subunit B,
— Both
LmjF.22.0530 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— Both
LmjF.02.0740 ⚠
dipeptylcarboxypeptidase, putative
— Both
LmjF.27.2660 ⚠
peptidyl dipeptidase, putative
— Both
LmjF.26.1570 ⚠
thimet oligopeptidase, putative
— Both
LmjF.04.0580 ⚠
spermidine synthase
— Both
LmjF.15.0520 ⚠
ecotin, putative
— Both
LmjF.06.1070 ⚠
deoxyribose-phosphate aldolase, putative
— Both
LmjF.21.1552 ⚠
ATP-dependent RNA helicase SUB2, putative
— Both
LmjF.19.0160 ⚠
metallo-peptidase, Clan MG, Family M24
— Both
LmjF.34.0160 ⚠
mitochondrial malate dehydrogenase
— Both
LmjF.36.6570 ⚠
y113g7b.23 protein-like protein
— Both
LmjF.34.0140 ⚠
malate dehydrogenase
— Both
LmjF.33.2520 ⚠
UDP-N-acetylglucosamine pyrophosphorylase, pu
— Both
LmjF.25.2340
AGC essential kinase 1
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.