LmjF.23.0310

hypothetical protein, conserved
Leishmania major strain Friedlin OG6: OG6_199886 OG7: OG7_0031195 89 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 89 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.34.2750 ⚠
methyltransferase-like protein
— OG7
LmjF.28.1820 ⚠
Replication factor A protein 1
— OG7
LmjF.06.0920 ⚠
hypothetical protein, conserved
— OG7
LmjF.26.1240 ⚠
heat shock protein 70-related protein
— OG7
LmjF.28.2780 ⚠
heat-shock protein hsp70, putative
— OG7
LmjF.18.1370 ⚠
heat shock protein 110, putative
— OG7
LmjF.28.2770 ⚠
heat-shock protein hsp70, putative
— OG7
LmjF.01.0640 ⚠
HSP70-like protein
— OG7
LmjF.26.0900 ⚠
heat shock 70 protein-like protein
— OG7
LmjF.28.1200 ⚠
luminal binding protein 1 (BiP), putative
— OG7
LmjF.35.4710 ⚠
170 kDa glucose-regulated protein, putative
— OG7
LmjF.31.2720 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.28.2010 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.1090 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.35.3260 ⚠
Peroxin 19
— OG7
LmjF.11.0420 ⚠
regulator of chromatin condensation, putative
— OG7
LmjF.34.4540 ⚠
13 kDa deflagellation-inducible protein, puta
— OG7
LmjF.30.2270 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.2020 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.36.4370 ⚠
ubiquitin protein ligase, putative
— OG7
LmjF.36.4030 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LmjF.35.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.17.0240 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.05.0230 ⚠
hydrogenase, putative
— OG7
LmjF.11.0150 ⚠
hypothetical protein, conserved
— OG7
LmjF.18.0700 ⚠
HEAT repeats, putative
— OG7
LmjF.29.1210 ⚠
hypothetical protein, conserved
— OG7
LmjF.22.1480 ⚠
Mitochondrial glycoprotein, putative
— OG7
LmjF.30.0970 ⚠
p22 protein precursor, putative
— OG7
LmjF.05.0790 ⚠
Mitochondrial glycoprotein, putative
— OG7
LmjF.09.1090 ⚠
translation initiation factor EIF-2B gamma su
— OG7
LmjF.09.1070 ⚠
eukaryotic translation initiation factor 2 su
— OG7
LmjF.20.0780 ⚠
Tubulin/FtsZ family, putative
— OG7
LmjF.30.0520 ⚠
N-acetyltransferase B complex (NatB) non cata
— OG7
LmjF.26.0740 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.26.0630 ⚠
hypothetical protein, conserved
— OG7
LmjF.21.0660 ⚠
nucleotide-binding protein, putative
— OG7
LmjF.26.0430 ⚠
nucleotide binding protein-like protein
— OG7
LmjF.07.0100 ⚠
metallo-peptidase, Clan ME, Family M16C
— OG7
LmjF.18.1150 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LmjF.10.1140 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LmjF.18.1570 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LmjF.09.1210 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LmjF.28.1220 ⚠
hypothetical protein, conserved
— OG7
LmjF.08.0550 ⚠
eukaryotic translation initiation factor 2 be
— OG7
LmjF.36.0190 ⚠
elongation factor 2
— OG7
LmjF.30.3080 ⚠
homoserine kinase
— OG7
LmjF.08.0310 ⚠
Isochorismatase family, putative
— OG7
LmjF.08.0320 ⚠
mitochondrial associated ribonuclease, putati
— OG7
LmjF.08.0300 ⚠
Isochorismatase family, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.