LmjF.28.2430

Vacuolar proton pump subunit B, putative
Leishmania major strain Friedlin OG6: OG6_100544 OG7: OG7_0005088 88 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 88 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.35.1180 ⚠
NADH-dependent fumarate reductase, putative
— +2 more Both
LmjF.36.3100
ATP synthase, putative
— Both
LmjF.07.0800 ⚠
flavoprotein subunit-like protein
— +2 more Both
LmjF.34.3670
vacuolar ATP synthase catalytic subunit A, pu
— Both
LmjF.35.1190 ⚠
NADH-dependent fumarate reductase, putative
— +2 more Both
LmjF.35.0830 ⚠
NADH-dependent fumarate reductase-like protei
— +2 more Both
LmjF.21.1340
ATP synthase, putative
— Both
LmjF.35.0700
vacuolar ATP synthase subunit d, putative
— Both
LmjF.21.0240 ⚠
hexokinase, putative
— Both
LmjF.24.2020
tubulin folding cofactor D, putative
— Both
LmjF.21.0250 ⚠
hexokinase, putative
— Both
LmjF.22.0650
guide RNA associated protein, GAP2, putative
— Both
LmjF.12.0520
vacuolar ATP synthase subunit, putative
— Both
LmjF.22.0590
Uncharacterised protein family UPF0066, putat
— Both
LmjF.03.0200
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
LmjF.21.1770
ATP synthase F1 subunit gamma protein, putati
— Both
LmjF.36.0150 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LmjF.23.0340
(H+)-ATPase G subunit, putative
— Both
LmjF.25.1170 ⚠
ATP synthase subunit beta, mitochondrial, put
— Both
LmjF.05.0500 ⚠
ATP synthase F1, alpha subunit, putative
— Both
LmjF.08.1130 ⚠
phosphoribosylpyrophosphate synthetase
— +1 more Both
LmjF.36.3910
S-adenosylhomocysteine hydrolase
— Both
LmjF.11.1000
pyruvate phosphate dikinase, putative
— Both
LmjF.30.3600
ATP synthase, epsilon chain, putative
— Both
LmjF.05.0510 ⚠
ATP synthase F1, alpha subunit, putative
— Both
LmjF.08.0510 ⚠
ribose-phosphate pyrophosphokinase, putative
— +1 more Both
LmjF.36.0490 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LmjF.19.1480 ⚠
eukaryotic translation initiation factor-like
— OG7
LmjF.14.0830 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.05.0850 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LmjF.19.1020 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LmjF.14.1070 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.27.1620 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LmjF.26.0420 ⚠
pseudouridylate synthase-like protein
— OG7
LmjF.36.4250 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.10.0160
hypothetical protein, conserved
— OG7
LmjF.24.0020
clathrin coat assembly protein, putative
— OG7
LmjF.30.0450 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
LmjF.29.0290 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LmjF.36.0080 ⚠
leucine carboxyl methyltransferase, putative
— OG7
LmjF.30.1550 ⚠
pseudouridine synthase A-like protein, putati
— OG7
LmjF.31.1370
hypothetical protein, conserved
— OG7
LmjF.19.1500 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
LmjF.15.0180 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.33.1830 ⚠
dual specificity tyrosine-phosphorylation-reg
— OG7
LmjF.35.1860 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.36.5390 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +2 more Both
LmjF.28.2770 ⚠
heat-shock protein hsp70, putative
— OG6
LmjF.21.1650 ⚠
protein kinase PK4, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.