LmjF.28.0890

ribonucleoside-diphosphate reductase large chain, putative
Leishmania major strain Friedlin OG6: OG6_100448 OG7: OG7_0004229 106 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 106 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.36.6780 ⚠
nuclear lim interactor-interacting factor, pu
— OG7
LmjF.05.0830
methylthioadenosine phosphorylase, putative
— Both
LmjF.10.0290
isocitrate dehydrogenase [NADP], mitochondria
— Both
LmjF.35.3340
6-phosphogluconate dehydrogenase, decarboxyla
— Both
LmjF.25.0020
n-terminal acetyltransferase complex ard1 sub
— Both
LmjF.16.0540
aspartate carbamoyltransferase, putative
— Both
LmjF.30.0520
N-acetyltransferase B complex (NatB) non cata
— Both
LmjF.23.0690 ⚠
3-ketoacyl-CoA thiolase, putative
— Both
LmjF.05.0690
hypothetical protein, conserved
— Both
LmjF.11.0700
anion-transporting ATPase-like protein
— Both
LmjF.29.2210
leucine-rich repeat-containing protein
— Both
LmjF.33.0780 ⚠
NLI interacting factor-like phosphatase, puta
— Both
LmjF.33.2050
hypothetical protein, conserved
— Both
LmjF.30.3320
hypothetical protein, conserved
— Both
LmjF.33.1020
PSP1 C-terminal conserved region, putative
— Both
LmjF.36.4780
paraflagellar rod component, putative
— Both
LmjF.32.1790
hypothetical protein, conserved
— Both
LmjF.36.4930
translation initiation factor 2 subunit, puta
— Both
LmjF.31.0010
5-methyltetrahydropteroyltriglutamate-homocys
— Both
LmjF.24.1730 ⚠
Calcium/calmodulin-dependent protein kinase k
— Both
LmjF.10.0840 ⚠
hypothetical protein, conserved
— Both
LmjF.28.0450 ⚠
DIS3-like exonuclease, putative
— Both
LmjF.28.0330 ⚠
rrp44p homologue, putative
— OG7
LmjF.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmjF.35.2160 ⚠
adenine aminohydrolase
— OG7
LmjF.30.2590 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.0100 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LmjF.15.1300 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.15.0240 ⚠
sterol carrier protein, putative
— OG7
LmjF.30.0700 ⚠
nuclear movement protein, putative
— OG7
LmjF.28.1770 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LmjF.35.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LmjF.32.1570 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LmjF.11.0620 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmjF.31.1130 ⚠
amidohydrolase, putative
— OG7
LmjF.18.1110 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LmjF.29.0330 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LmjF.17.1130 ⚠
NOL1/NOP2/sun family, putative
— OG7
LmjF.11.0630 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmjF.14.1370 ⚠
tyrosyl-tRNA synthetase, putative
— OG7
LmjF.35.0190 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LmjF.26.0160 ⚠
nuclear lim interactor-interacting factor-lik
— OG7
LmjF.25.2030 ⚠
mitochondrial import inner membrane transloca
— OG7
LmjF.35.3520 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LmjF.29.2400 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LmjF.35.2620 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
LmjF.11.0250 ⚠
Calcium/calmodulin-dependent protein kinase k
— OG7
LmjF.30.0735 ⚠
heat shock protein grpe
— OG7
LmjF.13.0710 ⚠
Putative GTPase activating protein for Arf, p
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.