LmjF.33.2540

metallo-peptidase, Clan MA(E) Family M32
Leishmania major strain Friedlin OG6: OG6_105939 OG7: OG7_0011443 25 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 25 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.29.1470 ⚠
hypothetical protein, conserved
— Both
LmjF.12.1250 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LmjF.29.2240 ⚠
Aminopeptidase M1, putative
— OG7
LmjF.17.0620 ⚠
Acyl CoA binding protein, putative
— OG7
LmjF.17.0780 ⚠
Acyl CoA binding protein, putative
— OG7
LmjF.34.2600 ⚠
acyl-CoA binding protein, putative
— OG7
LmjF.04.0990 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.3360 ⚠
Bromodomain factor 3, putative
— OG7
LmjF.36.6880 ⚠
Bromodomain factor 1
— OG7
LmjF.23.0760 ⚠
mitochondrial RNA binding protein, putative
— Both
LmjF.26.0300 ⚠
aminopeptidase-like protein
— Both
LmjF.31.0380 ⚠
hypothetical protein, conserved
— Both
LmjF.36.2360 ⚠
tyrosine aminotransferase
— Both
LmjF.28.1950 ⚠
X-pro, dipeptidyl-peptidase,serine peptidase,
— Both
LmjF.11.0100 ⚠
seryl-tRNA synthetase
— Both
LmjF.30.3300 ⚠
UV excision repair RAD23-like protein
— Both
LmjF.06.0860 ⚠
dihydrofolate reductase-thymidylate synthase
— Both
LmjF.36.2980 ⚠
bromodomain factor 2 protein, putative
— Both
LmjF.09.0750 ⚠
acyl-CoA binding protein, putative
— Both
LmjF.11.0350 ⚠
14-3-3 protein 2, putative
— Both
LmjF.27.2050 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LmjF.20.1190 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LmjF.22.1290 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LmjF.36.3210 ⚠
14-3-3 protein 1, putative
— Both
LmjF.35.0050 ⚠
2-oxoisovalerate dehydrogenase beta subunit,
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.