LmxM.04.0250

RNA pseudouridylate synthase-like protein
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_185520 OG7: OG7_0001865 93 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 93 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.28.0450 ⚠
DIS3-like exonuclease, putative
— OG7
LmxM.29.0470 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.6220 ⚠
flagellum transition zone component, putative
— OG7
LmxM.33.0310 ⚠
tRNA pseudouridine synthase, putative
— OG7
LmxM.30.1410 ⚠
hypothetical protein, conserved
— OG7
LmxM.08_29.1240 ⚠
Hsp70 protein/TPR repeat, putative
— OG7
LmxM.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmxM.08_29.2150 ⚠
cdc2-related kinase 10, putative
— OG7
LmxM.33.1150 ⚠
hypothetical protein, conserved
— OG7
LmxM.26.2320 ⚠
hypothetical protein, conserved
— OG7
LmxM.27.1680 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.1470 ⚠
EAP30/Vps36 family, putative
— OG7
LmxM.19.1020 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LmxM.18.0650 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
LmxM.29.1550 ⚠
pseudouridine synthase A-like protein, putati
— OG7
LmxM.10.0890 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LmxM.28.0330 ⚠
rrp44p homologue, putative
— OG7
LmxM.19.0750 ⚠
hypothetical protein, conserved
— OG7
LmxM.20.0940 ⚠
cyclophilin 15, putative
— OG7
LmxM.26.0420 ⚠
pseudouridylate synthase-like protein
— OG7
LmxM.29.3070 ⚠
tRNA (Guanine-1)-methyltransferase, putative
— OG7
LmxM.28.1100 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.1490 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.0760 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.3630 ⚠
CYC2-like protein, putative
— OG7
LmxM.13.0260 ⚠
N-acetyltransferase subunit ARD1, putative
— OG7
LmxM.22.0450 ⚠
Acetyltransferase (GNAT) family, putative
— OG7
LmxM.06.0685 ⚠
hypothetical protein, conserved
— OG7
LmxM.17.0940 ⚠
Phosphorylated CTD interacting factor 1 WW do
— OG7
LmxM.26.0470 ⚠
hypothetical protein, conserved
— OG7
LmxM.19.0220 ⚠
polyprenyl synthase, putative
— OG7
LmxM.17.1410 ⚠
zinc-finger protein ZPR1, putative
— OG7
LmxM.25.0800 ⚠
DNL zinc finger, putative
— OG7
LmxM.11.1120 ⚠
hypothetical protein
— OG7
LmxM.31.0820 ⚠
CYC2-like cyclin, putative
— OG7
LmxM.24.1880 ⚠
cyclin 11, putative
— OG7
LmxM.25.0870 ⚠
protein kinase, putative
— OG7
LmxM.24.1890 ⚠
cyclin 10
— OG7
LmxM.32.0770 ⚠
G1 cyclin CycE4, putative
— OG7
LmxM.05.0710 ⚠
CYC2-like cyclin, putative
— OG7
LmxM.36.6430 ⚠
protein transport protein Sec23-like protein
— OG7
LmxM.10.0310 ⚠
protein transport protein SEC23, putative
— OG7
LmxM.17.1310 ⚠
methyltransferase domain containing protein,
— OG7
LmxM.07.0831 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.0460 ⚠
hypothetical protein, unknown function
— OG7
LmxM.07.0840 ⚠
hypothetical protein, conserved
— OG7
LmxM.07.0830 ⚠
hypothetical protein, conserved
— OG7
LmxM.05.0460 ⚠
GTPase, putative
— OG7
LmxM.34.1310 ⚠
histone H4
— OG7
LmxM.36.0020 ⚠
histone H4
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.