LmxM.28.0450

DIS3-like exonuclease, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_102526 OG7: OG7_0002439 241 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 241 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.34.4550 ⚠
hypothetical protein, conserved
— +1 more Both
LmxM.29.1380 ⚠
amidohydrolase, putative
— Both
LmxM.14.1360 ⚠
myo-inositol-1-phosphate synthase
— +1 more Both
LmxM.11.0620 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmxM.30.1130 ⚠
amidohydrolase, putative
— Both
LmxM.25.0870 ⚠
protein kinase, putative
— +1 more Both
LmxM.32.1400 ⚠
protein kinase, putative
— OG7
LmxM.11.0630 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmxM.15.0690 ⚠
hypothetical protein, conserved
— Both
LmxM.20.1550 ⚠
amidohydrolase, putative
— Both
LmxM.20.1570 ⚠
amidohydrolase, putative
— Both
LmxM.20.1560 ⚠
amidohydrolase, putative
— Both
LmxM.32.2570 ⚠
metallo-peptidase, Clan MF, Family M17
— +1 more Both
LmxM.36.6080 ⚠
rab-like GTPase activating protein, putative
— OG7
LmxM.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmxM.36.0900 ⚠
SNF1-related protein kinases, putative (fragm
— OG7
LmxM.33.3550 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LmxM.18.1110 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LmxM.26.0580 ⚠
Protein of unknown function (DUF525), putativ
— OG7
LmxM.34.4260 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.1930 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmxM.28.2000 ⚠
phosphorylase kinase-like protein
— OG7
LmxM.34.3070 ⚠
hypothetical protein, conserved
— OG7
LmxM.08_29.0760 ⚠
heat shock protein 90, putative
— OG7
LmxM.33.1400 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— OG7
LmxM.25.1730 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.4280 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmxM.07.0900 ⚠
protein kinase, putative, serine/threonine ki
— OG7
LmxM.15.0980 ⚠
DNA repair protein Rad9, putative
— OG7
LmxM.18.0220 ⚠
RNA-binding protein 29, putative
— OG7
LmxM.18.1040 ⚠
putative 5-oxoprolinase, putative
— OG7
LmxM.21.0040 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.1400 ⚠
The ARF-like 2 binding protein BART, putative
— OG7
LmxM.29.0735 ⚠
co-chaperone, GrpE, putative, heat shock prot
— OG7
LmxM.04.0520 ⚠
huntingtin interacting protein (HIP), putativ
— OG7
LmxM.17.1130 ⚠
NOL1/NOP2/sun family, putative
— OG7
LmxM.03.0160 ⚠
ABC transporter protein, putative
— OG7
LmxM.29.2840 ⚠
GTPase activator-like protein
— OG7
LmxM.26.1260 ⚠
hypothetical protein, unknown function
— OG7
LmxM.07.0280 ⚠
HECT E3 ligase, putative
— OG7
LmxM.32.0316 ⚠
heat shock protein 83-1
— OG7
LmxM.21.0950 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LmxM.36.0470 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LmxM.34.5390 ⚠
HECT E3 ligase, putative
— OG7
LmxM.18.1330 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
LmxM.32.0140 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmxM.03.0480 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LmxM.32.0312 ⚠
heat shock protein 83-1
— OG7
LmxM.36.6350 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmxM.19.0980 ⚠
FYVE zinc finger, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.