LmxM.33.1400

d-isomer specific 2-hydroxyacid dehydrogenase- like protein
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_103299 OG7: OG7_0001275 70 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 70 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.36.2250 ⚠
developmentally regulated GTP-binding protein
— Both
LmxM.18.1330 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
LmxM.28.0450 ⚠
DIS3-like exonuclease, putative
— OG7
LmxM.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmxM.08_29.1100 ⚠
Ankyrin repeats (3 copies), putative
— Both
LmxM.23.1630 ⚠
hypothetical protein, conserved
— Both
LmxM.36.6350 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmxM.04.0580 ⚠
spermidine synthase, putative
— Both
LmxM.34.3070 ⚠
hypothetical protein, conserved
— Both
LmxM.34.5310 ⚠
GTP-binding protein, putative
— OG7
LmxM.18.0220 ⚠
RNA-binding protein 29, putative
— Both
LmxM.13.0550 ⚠
Uncharacterized ACR, COG1678, putative
— Both
LmxM.36.1400 ⚠
The ARF-like 2 binding protein BART, putative
— Both
LmxM.07.0100 ⚠
pitrilysin-like metalloprotease, metallo-pept
— Both
LmxM.22.0320 ⚠
SEP domain containing protein, putative
— +2 more Both
LmxM.32.2610 ⚠
Mitochondrial-processing peptidase subunit al
— Both
LmxM.11.0700 ⚠
anion-transporting ATPase-like protein
— Both
LmxM.24.2060 ⚠
transketolase, putative
— +2 more Both
LmxM.28.1740 ⚠
NOL1/NOP2/sun family, putative
— OG7
LmxM.04.0520 ⚠
huntingtin interacting protein (HIP), putativ
— OG7
LmxM.18.1100 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmxM.29.3260 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmxM.32.0140 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmxM.03.0480 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LmxM.34.2670 ⚠
ankyrin repeat protein, putative
— OG7
LmxM.33.4280 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmxM.26.2000 ⚠
methyltransferase domain containing protein,
— OG7
LmxM.11.0390 ⚠
hypothetical protein, conserved
— Both
LmxM.30.0190 ⚠
nucleolar protein, putative
— OG7
LmxM.08_29.2000 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.1500 ⚠
Protein of unknown function (DUF3808), putati
— OG7
LmxM.33.3550 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LmxM.34.2340 ⚠
ribonuclease, putative
— OG7
LmxM.21.0340 ⚠
metallo-peptidase, Clan ME, Family M16, mitoc
— OG7
LmxM.13.0870 ⚠
metallo-peptidase, Clan ME, Family M16, mitoc
— OG7
LmxM.26.0630 ⚠
hypothetical protein, conserved
— Both
LmxM.26.0580 ⚠
Protein of unknown function (DUF525), putativ
— Both
LmxM.25.1730 ⚠
hypothetical protein, conserved
— Both
LmxM.31.0890 ⚠
ethanolamine-phosphate cytidylyltransferase
— Both
LmxM.34.2300 ⚠
hypothetical protein, conserved
— Both
LmxM.08_29.2570 ⚠
serine/threonine-protein kinase, putative
— OG6
LmxM.33.1410 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— +2 more Both
LmxM.33.1415 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— +2 more Both
LmxM.14.1160 ⚠
enolase
— +2 more Both
LmxM.24.0190 ⚠
hypothetical protein, conserved
— Both
LmxM.24.1490 ⚠
WD domain, G-beta repeat, putative
— Both
LmxM.31.0960 ⚠
ubiquitin-conjugating enzyme protein, putativ
— Both
LmxM.36.1960 ⚠
phosphomannomutase, putative
— +2 more Both
LmxM.04.1190 ⚠
tRNA nucleotidyltransferase, putative
— Both
LmxM.28.0330 ⚠
rrp44p homologue, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.