LmxM.36.6350

poly(A)-specific ribonuclease PARN, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_102215 OG7: OG7_0005534 207 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 207 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.33.2340 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LmxM.18.1040 ⚠
putative 5-oxoprolinase, putative
— Both
LmxM.24.2020 ⚠
tubulin folding cofactor D, putative
— Both
LmxM.20.0280 ⚠
developmentally regulated phosphoprotein-like
— Both
LmxM.33.3900 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LmxM.29.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— +1 more Both
LmxM.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.19.1040 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
LmxM.12.0250 ⚠
cysteinyl-tRNA synthetase, putative
— Both
LmxM.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmxM.21.0340 ⚠
metallo-peptidase, Clan ME, Family M16, mitoc
— OG7
LmxM.13.0870 ⚠
metallo-peptidase, Clan ME, Family M16, mitoc
— OG7
LmxM.29.0910 ⚠
HECT E3 ligase, putative
— OG7
LmxM.29.1090 ⚠
WW domain containing protein, putative
— OG7
LmxM.07.0280 ⚠
HECT E3 ligase, putative
— OG7
LmxM.34.5390 ⚠
HECT E3 ligase, putative
— OG7
LmxM.20.0790 ⚠
tubulin-tyrosine ligase, putative
— OG7
LmxM.11.0400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LmxM.11.0380 ⚠
Domain of unknown function(DUF2779), putative
— OG7
LmxM.27.2490 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.08_29.1780 ⚠
diphthamide synthesis protein, putative
— OG7
LmxM.16.0380 ⚠
tubulin tyrosine ligase, putative
— OG7
LmxM.29.2280 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.31.2930 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.33.4030 ⚠
geranylgeranyltransferase, putative
— OG7
LmxM.08_29.0260 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LmxM.28.0160 ⚠
RNA binding protein, putative
— OG7
LmxM.18.0370 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LmxM.34.4930 ⚠
tubulin tyrosine ligase, putative
— OG7
LmxM.36.1260 ⚠
fructose-1,6-bisphosphate aldolase
— OG7
LmxM.08_29.0020 ⚠
transcription factor-like protein
— Both
LmxM.34.1470 ⚠
choline/ethanolamine kinase, putative
— Both
LmxM.07.0100 ⚠
pitrilysin-like metalloprotease, metallo-pept
— Both
LmxM.05.0180 ⚠
dihydrolipoamide branched chain transacylase,
— Both
LmxM.09.0740 ⚠
ubiquitin ligase, putative
— Both
LmxM.29.0560 ⚠
hypothetical protein, conserved
— Both
LmxM.23.1165 ⚠
coronin, putative
— Both
LmxM.32.0312 ⚠
heat shock protein 83-1
— +2 more Both
LmxM.34.0700 ⚠
vacuolar ATP synthase subunit d, putative
— Both
LmxM.36.4230 ⚠
paraflagellar rod component, putative
— OG6
LmxM.19.0260 ⚠
C-terminal motor kinesin, putative
— OG6
LmxM.31.0870 ⚠
phenylalanyl-tRNA synthetase alpha chain, put
— Both
LmxM.26.1900 ⚠
hypothetical protein, conserved
— Both
LmxM.32.0316 ⚠
heat shock protein 83-1
— +2 more Both
LmxM.01.0160 ⚠
LSM domain containing protein, putative
— OG7
LmxM.29.1205 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LmxM.34.4460 ⚠
sm-f snRNP core complex protein, putative
— OG7
LmxM.25.1705 ⚠
LSM domain containing protein, putative
— OG7
LmxM.31.1070 ⚠
small nuclear ribonucleoprotein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.