LmxM.24.2020

tubulin folding cofactor D, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_102599 OG7: OG7_0006853 207 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 207 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.18.1210 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— +2 more Both
LmxM.08.0410
WD domain, G-beta repeat, putative
— Both
LmxM.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— Both
LmxM.29.0460 ⚠
aspartyl-tRNA synthetase, putative
— Both
LmxM.20.0280 ⚠
developmentally regulated phosphoprotein-like
— Both
LmxM.18.1220 ⚠
prolyl-tRNA synthetase, putative,bifunctional
— +2 more Both
LmxM.19.1040
phenylalanyl-tRNA synthetase, putative
— Both
LmxM.34.2340 ⚠
ribonuclease, putative
— OG7
LmxM.33.3900 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LmxM.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— +1 more Both
LmxM.29.0560
hypothetical protein, conserved
— Both
LmxM.36.6350 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmxM.33.2340 ⚠
asparaginyl-tRNA synthetase, putative
— +1 more Both
LmxM.12.0250
cysteinyl-tRNA synthetase, putative
— Both
LmxM.23.1630 ⚠
hypothetical protein, conserved
— Both
LmxM.28.0680 ⚠
Ankyrin repeats (3 copies), putative
— OG6
LmxM.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmxM.19.1020 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LmxM.27.1620 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LmxM.10.0195 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.6710 ⚠
replication factor C subunit 3, putative
— OG7
LmxM.34.3250 ⚠
replication factor C, subunit 3, putative
— OG7
LmxM.20.1090 ⚠
hypothetical protein, conserved
— OG7
LmxM.17.0540 ⚠
ATPase family associated with various cellula
— OG7
LmxM.29.2630 ⚠
replication factor C, subunit 2, putative
— OG7
LmxM.27.0550 ⚠
replication factor C, subunit 4, putative
— OG7
LmxM.29.0910 ⚠
HECT E3 ligase, putative
— OG7
LmxM.33.4290
nucleolar protein family a, putative
— Both
LmxM.29.1090 ⚠
WW domain containing protein, putative
— OG7
LmxM.07.0280 ⚠
HECT E3 ligase, putative
— OG7
LmxM.34.5390 ⚠
HECT E3 ligase, putative
— OG7
LmxM.24.0490
Leucine Rich repeats (2 copies)/Leucine rich
— Both
LmxM.22.0650
guide RNA associated protein, GAP2, putative
— Both
LmxM.18.1040
putative 5-oxoprolinase, putative
— Both
LmxM.12.0510 ⚠
WW domain containing protein, putative
— Both
LmxM.01.0610
DNA-damage inducible protein DDI1-like protei
— Both
LmxM.21.1650 ⚠
protein kinase, putative
— Both
LmxM.20.1185 ⚠
calpain-like cysteine peptidase, putative
— OG6
LmxM.09.0740
ubiquitin ligase, putative
— Both
LmxM.36.4230
paraflagellar rod component, putative
— OG6
LmxM.28.2780 ⚠
heat-shock protein hsp70, putative
— OG6
LmxM.15.0660
hypothetical protein, conserved
— Both
LmxM.32.0312 ⚠
heat shock protein 83-1
— +2 more Both
LmxM.18.1320
hypothetical protein, conserved
— Both
LmxM.34.2940 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
LmxM.03.0910 ⚠
inorganic pyrophosphatase, putative
— Both
LmxM.05.0180
dihydrolipoamide branched chain transacylase,
— Both
LmxM.34.0700
vacuolar ATP synthase subunit d, putative
— Both
LmxM.28.2770 ⚠
heat-shock protein hsp70, putative
— OG6
LmxM.26.1240 ⚠
heat shock protein 70-related protein
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.