LmxM.36.6710

replication factor C subunit 3, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_102480 OG7: OG7_0001167 125 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 125 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.13.0620 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.2450 ⚠
HECT E3 ligase, putative
— OG7
LmxM.34.3360 ⚠
Putative death-receptor fusion protein (DUF24
— OG7
LmxM.29.2440 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.1040 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.4810 ⚠
BRCA1 C Terminus (BRCT) domain containing pro
— OG7
LmxM.32.0410 ⚠
DNA mismatch repair protein MSH2, putative
— OG7
LmxM.26.1180 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.0760 ⚠
cyclin 9, putative
— OG7
LmxM.33.2760 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.2340 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LmxM.26.1650 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.1070 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LmxM.36.4370 ⚠
HECT E3 ligase, putative
— OG7
LmxM.20.1100 ⚠
MORN repeat-containing protein
— OG7
LmxM.34.2770 ⚠
hypothetical protein, conserved
— OG7
LmxM.24.2020 ⚠
tubulin folding cofactor D, putative
— OG7
LmxM.26.1220 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.2460 ⚠
hypothetical protein, conserved
— OG7
LmxM.11.0060 ⚠
protein kinase, putative
— OG7
LmxM.33.2150 ⚠
eukaryotic translation initiation factor 2-al
— OG7
LmxM.01.0710 ⚠
ubiquitin activating enzyme, putative
— OG7
LmxM.08.0220 ⚠
ubiquitin-activating enzyme-like protein
— OG7
LmxM.34.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.15.1300 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.33.4060 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.08.0910 ⚠
Beta-lactamase superfamily domain containing
— OG7
LmxM.19.1050 ⚠
hypothetical protein, unknown function
— OG7
LmxM.12.0510 ⚠
WW domain containing protein, putative
— OG7
LmxM.28.2390 ⚠
WW domain containing protein, putative
— OG7
LmxM.17.1140 ⚠
WW domain containing protein, putative
— OG7
LmxM.21.0875 ⚠
hypothetical protein, conserved
— OG7
LmxM.19.1040 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
LmxM.19.0650 ⚠
hypothetical protein, conserved
— OG7
LmxM.23.0320 ⚠
hypothetical protein, conserved
— OG7
LmxM.23.0543 ⚠
5'-3' exoribonuclease C, putative
— OG7
LmxM.09.1100 ⚠
hypothetical protein, conserved
— OG7
LmxM.11.0930 ⚠
hypothetical protein, conserved
— OG7
LmxM.12.0250 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
LmxM.36.1955 ⚠
TLD, putative
— OG7
LmxM.06.0940 ⚠
hypothetical protein, conserved
— OG7
LmxM.03.0450 ⚠
TLD domain protein, conserved
— OG7
LmxM.20.0820 ⚠
hypothetical protein, conserved
— OG7
LmxM.08.0410 ⚠
WD domain, G-beta repeat, putative
— OG7
LmxM.15.0520 ⚠
ecotin, putative
— OG7
LmxM.15.0300 ⚠
Ecotin-like protein
— OG7
LmxM.03.0690 ⚠
DEAD/DEAH box helicase, putative
— OG7
LmxM.36.3000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmxM.22.0650 ⚠
guide RNA associated protein, GAP2, putative
— OG7
LmxM.09.1510 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.