LmxM.03.0690

DEAD/DEAH box helicase, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_105684 OG7: OG7_0002665 151 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 151 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.27.1620 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LmxM.02.0140 ⚠
Ankyrin repeats (3 copies)/Zinc finger, C3HC4
— Both
LmxM.34.2270
ATP-dependent RNA helicase-like protein
— OG6
LmxM.27.0190 ⚠
proteasome alpha 7 subunit, putative
— +1 more Both
LmxM.02.0310 ⚠
paraflagellar rod component, putative
— Both
LmxM.30.2970 ⚠
acetyl-CoA carboxylase
— Both
LmxM.11.0240 ⚠
proteasome alpha 7 subunit, putative
— +1 more Both
LmxM.28.0110 ⚠
proteasome beta 3 subunit, putative
— Both
LmxM.07.0090 ⚠
cobalamin-dependent methionine synthase, puta
— OG7
LmxM.03.0170 ⚠
hypothetical protein
— OG7
LmxM.31.2150 ⚠
hypothetical protein, conserved
— OG7
LmxM.07.0720 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.3060 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LmxM.36.0180 ⚠
elongation factor 2
— OG7
LmxM.23.0550 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LmxM.25.2080 ⚠
elongation factor 2-like protein
— OG7
LmxM.31.2200 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
LmxM.20.0500 ⚠
hypothetical protein, conserved
— OG7
LmxM.05.1010 ⚠
methyltransferase-like protein
— OG7
LmxM.14.0310 ⚠
proteasome alpha 3 subunit, putative
— OG7
LmxM.36.1600 ⚠
proteasome subunit alpha type-1, putative
— OG7
LmxM.08.0510 ⚠
ribose-phosphate pyrophosphokinase, putative
— OG7
LmxM.34.3860 ⚠
T-complex protein 1, eta subunit, putative
— OG7
LmxM.13.1660 ⚠
chaperonin TCP20, putative
— OG7
LmxM.21.1830 ⚠
proteasome subunit alpha type-5, putative
— OG7
LmxM.36.6910 ⚠
T-complex protein 1, theta subunit, putative
— OG7
LmxM.27.1260 ⚠
T-complex protein 1, beta subunit, putative
— OG7
LmxM.36.1650 ⚠
proteasome subunit beta type-5, putative
— OG7
LmxM.34.2300 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.0180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
LmxM.25.1020 ⚠
dehydrogenase-like protein
— OG7
LmxM.32.1890 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.4210 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.2730 ⚠
acyl-CoA dehydrogenase, putative
— OG7
LmxM.32.0150 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.3500 ⚠
zinc finger protein, putative
— OG7
LmxM.10.0195 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.0310 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LmxM.34.4260 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.0730 ⚠
Outer row dynein-assembly protein 7
— OG7
LmxM.29.0910 ⚠
HECT E3 ligase, putative
— OG7
LmxM.34.3250 ⚠
replication factor C, subunit 3, putative
— OG7
LmxM.26.1420 ⚠
FYVE zinc finger, putative
— OG7
LmxM.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.36.6710 ⚠
replication factor C subunit 3, putative
— OG7
LmxM.19.1480 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
LmxM.28.2500 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LmxM.32.0200 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LmxM.36.1955 ⚠
TLD, putative
— OG7
LmxM.36.2440 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.