LmxM.29.0180

2-hydroxy-3-oxopropionate reductase, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_101839 OG7: OG7_0002731 213 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 213 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.13.0730 ⚠
ubiquitin-like protein
— Both
LmxM.27.0720 ⚠
UBA/TS-N domain containing protein, putative
— Both
LmxM.36.0540 ⚠
ubiquitin-like protein, putative
— OG7
LmxM.36.0180 ⚠
elongation factor 2
— OG7
LmxM.32.1710 ⚠
protein kinase, putative
— OG7
LmxM.36.3280 ⚠
Enoyl-CoA hydratase/isomerase family/2-enoyl-
— OG7
LmxM.17.1150 ⚠
5'-3' exoribonuclease B, putative
— OG7
LmxM.28.1340 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LmxM.28.1360 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmxM.28.1350 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmxM.28.1380 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmxM.21.1620 ⚠
mitochondrial RNA binding complex 1 subunit,
— OG7
LmxM.32.2510 ⚠
Mitochondrial SSU ribosomal protein, putative
— OG7
LmxM.27.1030 ⚠
hypothetical protein, conserved
— OG7
LmxM.03.0060 ⚠
Met-10+ like-protein, putative
— OG7
LmxM.30.2880 ⚠
aldehyde reductase, putative
— OG7
LmxM.27.2410 ⚠
aldo-keto reductase-like protein
— OG7
LmxM.27.1895 ⚠
hypothetical protein, conserved
— OG7
LmxM.08.0870 ⚠
hypothetical protein, unknown function
— OG7
LmxM.03.0220 ⚠
hypothetical protein, conserved
— OG7
LmxM.08.1100 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.2660 ⚠
hypothetical protein, conserved
— OG7
LmxM.15.0290 ⚠
hypothetical protein, conserved
— OG7
LmxM.05.0860 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.3490 ⚠
hypothetical protein, conserved
— OG7
LmxM.04.0045 ⚠
hypothetical protein, conserved
— OG7
LmxM.16.0160 ⚠
50S ribosomal protein L17, putative
— OG7
LmxM.26.2270 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.0140 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
LmxM.34.3060 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LmxM.36.2440 ⚠
hypothetical protein, conserved
— Both
LmxM.34.0750 ⚠
proteasome activator protein pa26, putative
— Both
LmxM.25.2080 ⚠
elongation factor 2-like protein
— Both
LmxM.14.0910 ⚠
glutathione synthetase, putative
— Both
LmxM.28.1110 ⚠
WD domain, G-beta repeat, putative
— Both
LmxM.28.1140 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
LmxM.23.1480 ⚠
alanine racemase, putative
— Both
LmxM.22.0320 ⚠
SEP domain containing protein, putative
— Both
LmxM.28.1370 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
LmxM.24.0370 ⚠
aspartate aminotransferase, putative
— Both
LmxM.34.0820 ⚠
aspartate aminotransferase, putative
— Both
LmxM.13.0780 ⚠
protein kinase, putative
— Both
LmxM.36.3350 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.2060 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LmxM.13.0140 ⚠
hypothetical protein, conserved
— OG7
LmxM.13.0130 ⚠
Kinesin-13 2
— OG7
LmxM.01.0030 ⚠
Kinesin-13 1, putative
— OG7
LmxM.30.0290 ⚠
Kinesin-13 4, putative
— OG7
LmxM.13.1610 ⚠
Kinesin-13 5, putative
— OG7
LmxM.16.0310 ⚠
Met-10+ like-protein, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.