LmxM.27.0720

UBA/TS-N domain containing protein, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_129093 OG7: OG7_0004831 151 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 151 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.29.0180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
LmxM.25.1020 ⚠
dehydrogenase-like protein
— OG7
LmxM.16.0310 ⚠
Met-10+ like-protein, putative
— OG7
LmxM.32.0090 ⚠
hypothetical protein, conserved
— Both
LmxM.08_29.0340 ⚠
UBX domain-containing protein
— Both
LmxM.10.0290 ⚠
isocitrate dehydrogenase [NADP]
— Both
LmxM.12.0020 ⚠
PITH domain-containing protein
— Both
LmxM.18.0210 ⚠
Activator of Hsp90 ATPase, N-terminal/Activat
— Both
LmxM.30.1070 ⚠
biotin/lipoate protein ligase-like protein
— Both
LmxM.21.0640 ⚠
phosphoglucomutase, putative
— Both
LmxM.18.0640 ⚠
serine/threonine kinase-like protein, putativ
— Both
LmxM.36.3580 ⚠
Protein of unknown function (DUF2009), putati
— Both
LmxM.34.0030 ⚠
pyruvate kinase, putative
— Both
LmxM.31.0080 ⚠
N-myristoyl transferase, putative
— Both
LmxM.08_29.0780 ⚠
U-box domain protein, putative
— Both
LmxM.34.4470 ⚠
Co-chaperone protein P23
— Both
LmxM.27.1620 ⚠
Eukaryotic translation initiation factor 4E-1
— Both
LmxM.36.3690 ⚠
Nucleoporin NUP119
— Both
LmxM.34.0020 ⚠
pyruvate kinase
— Both
LmxM.25.2020 ⚠
hypothetical protein, conserved
— Both
LmxM.18.0610
ATP-dependent zinc metallopeptidase, putative
— OG6
LmxM.14.1190 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— Both
LmxM.16.0580 ⚠
dihydroorotase, putative
— Both
LmxM.20.1580 ⚠
hypothetical protein, conserved
— Both
LmxM.11.0210 ⚠
acidocalcisomal pyrophosphatase
— Both
LmxM.03.0910 ⚠
inorganic pyrophosphatase, putative
— Both
LmxM.13.1610 ⚠
Kinesin-13 5, putative
— OG7
LmxM.30.0290 ⚠
Kinesin-13 4, putative
— OG7
LmxM.01.0030 ⚠
Kinesin-13 1, putative
— OG7
LmxM.13.0130 ⚠
Kinesin-13 2
— OG7
LmxM.32.2410 ⚠
diphthamide biosynthesis enzyme Dph1/Dph2 dom
— OG7
LmxM.32.3670 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LmxM.31.3650 ⚠
hypothetical protein
— OG7
LmxM.08.0870 ⚠
hypothetical protein, unknown function
— OG7
LmxM.27.2410 ⚠
aldo-keto reductase-like protein
— OG7
LmxM.30.2880 ⚠
aldehyde reductase, putative
— OG7
LmxM.11.1000 ⚠
pyruvate phosphate dikinase, putative
— OG7
LmxM.34.3060 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LmxM.34.0750 ⚠
proteasome activator protein pa26, putative
— OG7
LmxM.28.2500 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LmxM.07.0870 ⚠
splicing factor ptsr1-like protein
— OG7
LmxM.32.1710 ⚠
protein kinase, putative
— OG7
LmxM.06.0510 ⚠
U-box domain containing protein, putative
— OG7
LmxM.28.1960 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
LmxM.31.2450 ⚠
Cid1 family poly A polymerase, putative
— OG7
LmxM.21.1740 ⚠
RNA polymerase II, putative
— OG7
LmxM.29.0450 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
LmxM.19.1480 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
LmxM.28.2000 ⚠
phosphorylase kinase-like protein
— OG7
LmxM.22.0340 ⚠
methylenetetrahydrofolate dehydrogenase-like
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.