LmxM.12.0020

PITH domain-containing protein
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_102988 OG7: OG7_0006444 192 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 192 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.28.1380 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmxM.30.0255 ⚠
hypothetical protein, conserved
— OG7
LmxM.28.1340 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LmxM.28.1350 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmxM.28.1360 ⚠
haloacid dehalogenase-like hydrolase-like pro
— Both
LmxM.28.1370 ⚠
haloacid dehalogenase-like hydrolase, putativ
— +1 more Both
LmxM.36.6180 ⚠
Sucrase/ferredoxin-like, putative
— Both
LmxM.33.0540
Gamma-soluble NSF attachment protein (SNAP-ga
— Both
LmxM.34.2410 ⚠
ubiquitin hydrolase, putative,cysteine peptid
— OG7
LmxM.30.2500 ⚠
ferredoxin, 2fe-2s-like protein, adrenodoxin-
— OG7
LmxM.31.3650 ⚠
hypothetical protein
— OG7
LmxM.32.3670 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LmxM.26.1420 ⚠
FYVE zinc finger, putative
— OG7
LmxM.14.1170 ⚠
hypothetical protein, conserved
— OG7
LmxM.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmxM.26.1260 ⚠
hypothetical protein, unknown function
— OG7
LmxM.34.3500 ⚠
zinc finger protein, putative
— OG7
LmxM.18.0600 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LmxM.34.4260 ⚠
hypothetical protein, conserved
— OG7
LmxM.13.0130 ⚠
Kinesin-13 2
— OG7
LmxM.01.0030 ⚠
Kinesin-13 1, putative
— OG7
LmxM.30.0290 ⚠
Kinesin-13 4, putative
— OG7
LmxM.13.1610 ⚠
Kinesin-13 5, putative
— OG7
LmxM.03.0910 ⚠
inorganic pyrophosphatase, putative
— Both
LmxM.11.0210 ⚠
acidocalcisomal pyrophosphatase
— Both
LmxM.27.0720 ⚠
UBA/TS-N domain containing protein, putative
— Both
LmxM.10.0290
isocitrate dehydrogenase [NADP]
— Both
LmxM.23.0150
hypothetical protein, conserved
— OG6
LmxM.10.0200
Mitogen-activated protein kinase 10, putative
— OG6
LmxM.10.0490
mitogen-activated protein kinase
— OG6
LmxM.36.0070 ⚠
stress-inducible protein STI1 homolog
— OG6
LmxM.36.0530 ⚠
protein phosphatase 2C-like protein
— OG6
LmxM.27.2390 ⚠
TPR-repeat protein, putative
— OG6
LmxM.31.1830 ⚠
iron superoxide dismutase, putative
— Both
LmxM.27.2320 ⚠
protein phosphatase-like protein
— OG6
LmxM.08.0480
hypothetical protein, conserved
— Both
LmxM.32.0090
hypothetical protein, conserved
— Both
LmxM.05.0310 ⚠
glutaredoxin-like protein
— Both
LmxM.08_29.0340
UBX domain-containing protein
— Both
LmxM.34.1250 ⚠
thioredoxin-like protein
— Both
LmxM.01.0220
cyclophilin type peptidyl-prolyl cis-trans is
— OG6
LmxM.28.2070
tRNA threonylcarbamoyl adenosine modification
— Both
LmxM.16.0580
dihydroorotase, putative
— Both
LmxM.14.1190
Bifunctional NAD(P)H-hydrate repair enzyme
— Both
LmxM.08.0290 ⚠
iron superoxide dismutase A, mitochondrial
— Both
LmxM.21.0640
phosphoglucomutase, putative
— Both
LmxM.31.1820 ⚠
iron superoxide dismutase, putative
— Both
LmxM.30.1070
biotin/lipoate protein ligase-like protein
— Both
LmxM.30.2510 ⚠
ferredoxin, 2fe-2s-like protein
— OG7
LmxM.18.0640 ⚠
serine/threonine kinase-like protein, putativ
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.