LmxM.28.1380

haloacid dehalogenase-like hydrolase-like protein
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_152033 OG7: OG7_0005628 166 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 166 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.12.0020 ⚠
PITH domain-containing protein
— OG7
LmxM.21.0030 ⚠
hypothetical protein, conserved
— OG7
LmxM.22.1030 ⚠
hypothetical protein, conserved
— OG7
LmxM.26.1570 ⚠
metallo-peptidase, Clan MA(E), Family M3, thi
— OG7
LmxM.36.0570 ⚠
Elongation factor G1, mitochondrial, putative
— OG7
LmxM.36.0890 ⚠
eukaryotic translation initiation factor 6 (e
— OG7
LmxM.29.0450 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
LmxM.36.4450 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LmxM.30.0140 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmxM.07.0900 ⚠
protein kinase, putative, serine/threonine ki
— OG7
LmxM.21.0040 ⚠
hypothetical protein, conserved
— OG7
LmxM.13.0730 ⚠
ubiquitin-like protein
— OG7
LmxM.18.0020 ⚠
diphosphomevalonate decarboxylase, putative
— OG7
LmxM.19.1480 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
LmxM.24.0480 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LmxM.15.0880 ⚠
myo-inositol-1 phosphatase, putative
— OG7
LmxM.33.2000 ⚠
pyroglutamyl-peptidase I, putative
— OG7
LmxM.28.2000 ⚠
phosphorylase kinase-like protein
— OG7
LmxM.25.2010 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— OG7
LmxM.32.3670 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LmxM.31.3650 ⚠
hypothetical protein
— OG7
LmxM.25.1290 ⚠
NPL4 family, putative
— OG7
LmxM.28.2500 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LmxM.25.1370 ⚠
TAP42-like family, putative
— OG7
LmxM.34.4160 ⚠
Protein of unknown function (DUF2009), putati
— OG7
LmxM.36.6170 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.0900 ⚠
SNF1-related protein kinases, putative (fragm
— OG7
LmxM.20.0600 ⚠
hypothetical protein, conserved
— OG7
LmxM.26.2700 ⚠
6-phosphogluconolactonase
— OG7
LmxM.36.4500 ⚠
Protein of unknown function (DUF2870), putati
— OG7
LmxM.33.0210 ⚠
CS domain containing protein, putative
— OG7
LmxM.28.2070 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
LmxM.08_29.1310 ⚠
carnitine/choline acetyltransferase, putative
— OG7
LmxM.01.0830 ⚠
hypothetical protein
— OG7
LmxM.08_29.2020 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
LmxM.31.2070 ⚠
cytidylyltransferase, putative
— OG7
LmxM.11.0210 ⚠
acidocalcisomal pyrophosphatase
— OG7
LmxM.20.0210 ⚠
kelch domain-containing protein
— OG7
LmxM.33.3970 ⚠
AP-1 adapter complex gamma subunit, putative
— OG7
LmxM.30.1610 ⚠
diphthine synthase-like protein
— OG7
LmxM.22.0810 ⚠
serine/threonine protein kinase sos2, putativ
— OG7
LmxM.21.0150 ⚠
serine/threonine-protein kinase-like protein
— OG7
LmxM.18.0990 ⚠
UTP-glucose-1-phosphate uridylyltransferase 2
— OG7
LmxM.34.3010 ⚠
trypanothione-dependent glyoxalase I, glyoxal
— OG7
LmxM.31.2910 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.12.0190 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.26.1050 ⚠
2Fe-2S iron-sulfur cluster binding domain con
— OG7
LmxM.30.2490 ⚠
adrenodoxin-like protein, ferredoxin, 2fe-2s-
— OG7
LmxM.36.6310 ⚠
homocysteine S-methyltransferase, putative
— OG7
LmxM.08_29.2210 ⚠
leucine-rich repeat-containing protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.