LmxM.10.0200

Mitogen-activated protein kinase 10, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_147455 OG7: OG7_0000396 116 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 116 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.24.0370 ⚠
aspartate aminotransferase, putative
— OG6
LmxM.14.1190
Bifunctional NAD(P)H-hydrate repair enzyme
— OG6
LmxM.18.0020
diphosphomevalonate decarboxylase, putative
— OG6
LmxM.08_29.1310
carnitine/choline acetyltransferase, putative
— OG6
LmxM.31.1100
exportin 1, putative
— OG6
LmxM.25.2020
hypothetical protein, conserved
— OG6
LmxM.31.2070 ⚠
cytidylyltransferase, putative
— OG6
LmxM.28.1110
WD domain, G-beta repeat, putative
— OG6
LmxM.18.0290 ⚠
dephospho-CoA kinase, putative
— OG6
LmxM.36.3990
ATP-dependent protease subunit HslV, putative
— OG6
LmxM.31.1690 ⚠
protein phosphatase 2C, putative
— OG6
LmxM.29.0380
phosphatase 2C, putative
— OG6
LmxM.36.0530 ⚠
protein phosphatase 2C-like protein
— OG6
LmxM.28.1140
electron-transfer-flavoprotein, alpha polypep
— OG6
LmxM.23.1480
alanine racemase, putative
— OG6
LmxM.22.0320
SEP domain containing protein, putative
— OG6
LmxM.27.2320 ⚠
protein phosphatase-like protein
— OG6
LmxM.16.0040
2OG-Fe(II) oxygenase superfamily, putative
— OG6
LmxM.25.2130 ⚠
succinyl-CoA synthetase alpha subunit, putati
— OG6
LmxM.25.2140 ⚠
succinyl-CoA synthetase alpha subunit, putati
— OG6
LmxM.07.0900 ⚠
protein kinase, putative, serine/threonine ki
— OG6
LmxM.32.0090
hypothetical protein, conserved
— OG6
LmxM.18.0640 ⚠
serine/threonine kinase-like protein, putativ
— OG6
LmxM.20.0600
hypothetical protein, conserved
— OG6
LmxM.21.0040
hypothetical protein, conserved
— OG6
LmxM.08_29.0340
UBX domain-containing protein
— OG6
LmxM.18.0210
Activator of Hsp90 ATPase, N-terminal/Activat
— OG6
LmxM.29.2610
RNA-binding protein, putative
— OG6
LmxM.28.1370
haloacid dehalogenase-like hydrolase, putativ
— OG6
LmxM.12.0020
PITH domain-containing protein
— OG6
LmxM.03.0910 ⚠
inorganic pyrophosphatase, putative
— OG6
LmxM.11.0210 ⚠
acidocalcisomal pyrophosphatase
— OG6
LmxM.27.0720
UBA/TS-N domain containing protein, putative
— OG6
LmxM.33.0540
Gamma-soluble NSF attachment protein (SNAP-ga
— OG6
LmxM.31.1820 ⚠
iron superoxide dismutase, putative
— OG6
LmxM.31.1830 ⚠
iron superoxide dismutase, putative
— OG6
LmxM.08.0290 ⚠
iron superoxide dismutase A, mitochondrial
— OG6
LmxM.31.2630 ⚠
superoxide dismutase, putative
— OG6
LmxM.01.0220
cyclophilin type peptidyl-prolyl cis-trans is
— OG6
LmxM.36.6180
Sucrase/ferredoxin-like, putative
— OG6
LmxM.28.2070
tRNA threonylcarbamoyl adenosine modification
— OG6
LmxM.36.0570
Elongation factor G1, mitochondrial, putative
— OG6
LmxM.27.2390 ⚠
TPR-repeat protein, putative
— OG6
LmxM.36.0070 ⚠
stress-inducible protein STI1 homolog
— OG6
LmxM.16.0580
dihydroorotase, putative
— OG6
LmxM.31.0910
Alpha/beta hydrolase family, putative
— OG6
LmxM.32.0960
nicotinate phosphoribosyltransferase, putativ
— OG6
LmxM.30.0140
ubiquitin carboxyl-terminal hydrolase, putati
— OG6
LmxM.28.0060
hypothetical protein, conserved
— OG6
LmxM.31.0080
N-myristoyl transferase, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.