LmxM.01.0220

cyclophilin type peptidyl-prolyl cis-trans isomerase, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_109053 OG7: OG7_0000556 93 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 93 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.27.2390 ⚠
TPR-repeat protein, putative
— OG6
LmxM.10.0290
isocitrate dehydrogenase [NADP]
— OG6
LmxM.03.0570
quinone oxidoreductase, putative
— OG6
LmxM.32.0960
nicotinate phosphoribosyltransferase, putativ
— OG6
LmxM.28.1220
hypothetical protein, conserved
— OG6
LmxM.08_29.0340
UBX domain-containing protein
— OG6
LmxM.26.1910
hypothetical protein, conserved
— OG6
LmxM.36.6650
2,3-bisphosphoglycerate-independentphosphogly
— OG6
LmxM.27.0720
UBA/TS-N domain containing protein, putative
— OG6
LmxM.32.0090
hypothetical protein, conserved
— OG6
LmxM.08.0480
hypothetical protein, conserved
— OG6
LmxM.27.2320 ⚠
protein phosphatase-like protein
— OG6
LmxM.12.0020
PITH domain-containing protein
— OG6
LmxM.33.3780
phosphomannomutase-like protein
— OG6
LmxM.36.0530 ⚠
protein phosphatase 2C-like protein
— OG6
LmxM.36.0070 ⚠
stress-inducible protein STI1 homolog
— OG6
LmxM.18.0290 ⚠
dephospho-CoA kinase, putative
— OG6
LmxM.31.0960
ubiquitin-conjugating enzyme protein, putativ
— OG6
LmxM.20.1690 ⚠
soluble n-ethylmaleimide sensitive factor, pu
— OG6
LmxM.31.1580
phosphomannose isomerase, putative
— OG6
LmxM.18.0990
UTP-glucose-1-phosphate uridylyltransferase 2
— OG6
LmxM.10.0200
Mitogen-activated protein kinase 10, putative
— OG6
LmxM.31.2070 ⚠
cytidylyltransferase, putative
— OG6
LmxM.11.0210 ⚠
acidocalcisomal pyrophosphatase
— OG6
LmxM.01.0090
UMP-CMP kinase, mitochondrial, putative
— OG6
LmxM.16.0580
dihydroorotase, putative
— OG6
LmxM.14.1190
Bifunctional NAD(P)H-hydrate repair enzyme
— OG6
LmxM.25.2020
hypothetical protein, conserved
— OG6
LmxM.31.0910
Alpha/beta hydrolase family, putative
— OG6
LmxM.31.2400
hypothetical protein, conserved
— OG6
LmxM.34.0020 ⚠
pyruvate kinase
— OG6
LmxM.31.3680
enoyl-CoA hydratase/isomerase family protein,
— OG6
LmxM.26.2370
HECT E3 ligase, putative
— OG6
LmxM.27.1620
Eukaryotic translation initiation factor 4E-1
— OG6
LmxM.34.4470 ⚠
Co-chaperone protein P23
— OG6
LmxM.08_29.0780
U-box domain protein, putative
— OG6
LmxM.08_29.1310
carnitine/choline acetyltransferase, putative
— OG6
LmxM.32.0730
WD domain, G-beta repeat, putative
— OG6
LmxM.34.0030 ⚠
pyruvate kinase, putative
— OG6
LmxM.36.3580 ⚠
Protein of unknown function (DUF2009), putati
— OG6
LmxM.31.0080
N-myristoyl transferase, putative
— OG6
LmxM.18.0640 ⚠
serine/threonine kinase-like protein, putativ
— OG6
LmxM.21.0640
phosphoglucomutase, putative
— OG6
LmxM.03.0760
hypothetical protein, conserved
— OG6
LmxM.03.0910 ⚠
inorganic pyrophosphatase, putative
— OG6
LmxM.18.0210
Activator of Hsp90 ATPase, N-terminal/Activat
— OG6
LmxM.30.1070
biotin/lipoate protein ligase-like protein
— OG6
LmxM.29.2600 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG6
LmxM.29.2610
RNA-binding protein, putative
— OG6
LmxM.22.0320
SEP domain containing protein, putative
— OG6
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.