LmxM.31.3680

enoyl-CoA hydratase/isomerase family protein, putative, 3-hydroxyisobutyryl-coenzyme A hydrolase, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_102025 OG7: OG7_0000750 141 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 141 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.16.0760 ⚠
transaldolase, putative
— Both
LmxM.06.0510 ⚠
U-box domain containing protein, putative
— OG7
LmxM.27.1620 ⚠
Eukaryotic translation initiation factor 4E-1
— Both
LmxM.34.0020 ⚠
pyruvate kinase
— Both
LmxM.25.2020 ⚠
hypothetical protein, conserved
— Both
LmxM.14.1190 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— Both
LmxM.16.0580 ⚠
dihydroorotase, putative
— Both
LmxM.08_29.1310 ⚠
carnitine/choline acetyltransferase, putative
— Both
LmxM.01.0770 ⚠
Eukaryotic initiation factor 4A-1
— Both
LmxM.31.2070 ⚠
cytidylyltransferase, putative
— Both
LmxM.28.1110 ⚠
WD domain, G-beta repeat, putative
— Both
LmxM.18.0290 ⚠
dephospho-CoA kinase, putative
— Both
LmxM.28.1140 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
LmxM.23.1480 ⚠
alanine racemase, putative
— Both
LmxM.22.0320 ⚠
SEP domain containing protein, putative
— Both
LmxM.29.2610
RNA-binding protein, putative
— OG6
LmxM.28.1370 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
LmxM.24.0370 ⚠
aspartate aminotransferase, putative
— Both
LmxM.34.0820 ⚠
aspartate aminotransferase, putative
— Both
LmxM.30.0140 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
LmxM.32.0960 ⚠
nicotinate phosphoribosyltransferase, putativ
— Both
LmxM.31.0910 ⚠
Alpha/beta hydrolase family, putative
— Both
LmxM.32.2810 ⚠
transcription elongation factor-like protein
— Both
LmxM.33.3780 ⚠
phosphomannomutase-like protein
— Both
LmxM.33.3470 ⚠
amidinotransferase, putative
— Both
LmxM.28.2070 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
LmxM.01.0220
cyclophilin type peptidyl-prolyl cis-trans is
— OG6
LmxM.11.0210 ⚠
acidocalcisomal pyrophosphatase
— Both
LmxM.03.0910 ⚠
inorganic pyrophosphatase, putative
— Both
LmxM.36.3660 ⚠
NUDIX hydrolase 3, putative
— OG7
LmxM.32.0550 ⚠
hypothetical protein, conserved
— OG7
LmxM.13.1610 ⚠
Kinesin-13 5, putative
— OG7
LmxM.30.0290 ⚠
Kinesin-13 4, putative
— OG7
LmxM.01.0030 ⚠
Kinesin-13 1, putative
— OG7
LmxM.13.0130 ⚠
Kinesin-13 2
— OG7
LmxM.32.1710 ⚠
protein kinase, putative
— OG7
LmxM.28.1380 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmxM.08.0870 ⚠
hypothetical protein, unknown function
— OG7
LmxM.27.2410 ⚠
aldo-keto reductase-like protein
— OG7
LmxM.30.2880 ⚠
aldehyde reductase, putative
— OG7
LmxM.29.0890 ⚠
adenosine kinase-like protein
— OG7
LmxM.33.3970 ⚠
AP-1 adapter complex gamma subunit, putative
— OG7
LmxM.07.0050 ⚠
alpha-adaptin-like protein
— OG7
LmxM.22.0310 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LmxM.19.1540 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LmxM.22.0340 ⚠
methylenetetrahydrofolate dehydrogenase-like
— OG7
LmxM.25.1020 ⚠
dehydrogenase-like protein
— OG7
LmxM.01.0210 ⚠
CUE domain/Domain of unknown function (DUF177
— OG7
LmxM.17.1150 ⚠
5'-3' exoribonuclease B, putative
— OG7
LmxM.24.0210 ⚠
transcription elongation factor, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.