LmxM.22.0340

methylenetetrahydrofolate dehydrogenase-like protein
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_200158 OG7: OG7_0002739 150 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 150 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.19.1480 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
LmxM.36.6640 ⚠
hypothetical protein, conserved
— OG7
LmxM.14.1170 ⚠
hypothetical protein, conserved
— OG7
LmxM.08.0480 ⚠
hypothetical protein, conserved
— OG7
LmxM.32.0090 ⚠
hypothetical protein, conserved
— OG7
LmxM.21.1740 ⚠
RNA polymerase II, putative
— OG7
LmxM.27.0720 ⚠
UBA/TS-N domain containing protein, putative
— OG7
LmxM.31.1830 ⚠
iron superoxide dismutase, putative
— OG7
LmxM.36.6650 ⚠
2,3-bisphosphoglycerate-independentphosphogly
— OG7
LmxM.26.1910 ⚠
hypothetical protein, conserved
— OG7
LmxM.05.0310 ⚠
glutaredoxin-like protein
— OG7
LmxM.08_29.0340 ⚠
UBX domain-containing protein
— OG7
LmxM.32.0960 ⚠
nicotinate phosphoribosyltransferase, putativ
— OG7
LmxM.19.1540 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LmxM.03.0570 ⚠
quinone oxidoreductase, putative
— OG7
LmxM.36.3880 ⚠
eukaryotic translation initiation factor 3 su
— OG7
LmxM.07.0050 ⚠
alpha-adaptin-like protein
— OG7
LmxM.17.1150 ⚠
5'-3' exoribonuclease B, putative
— OG7
LmxM.21.0500 ⚠
hypothetical protein, conserved
— OG7
LmxM.26.1420 ⚠
FYVE zinc finger, putative
— OG7
LmxM.10.0290 ⚠
isocitrate dehydrogenase [NADP]
— OG7
LmxM.12.0020 ⚠
PITH domain-containing protein
— OG7
LmxM.30.1070 ⚠
biotin/lipoate protein ligase-like protein
— OG7
LmxM.18.0210 ⚠
Activator of Hsp90 ATPase, N-terminal/Activat
— OG7
LmxM.25.1020 ⚠
dehydrogenase-like protein
— OG7
LmxM.31.1820 ⚠
iron superoxide dismutase, putative
— OG7
LmxM.36.6180 ⚠
Sucrase/ferredoxin-like, putative
— OG7
LmxM.03.0760 ⚠
hypothetical protein, conserved
— OG7
LmxM.03.0910 ⚠
inorganic pyrophosphatase, putative
— OG7
LmxM.36.0570 ⚠
Elongation factor G1, mitochondrial, putative
— OG7
LmxM.36.0890 ⚠
eukaryotic translation initiation factor 6 (e
— OG7
LmxM.29.0450 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
LmxM.31.2630 ⚠
superoxide dismutase, putative
— OG7
LmxM.30.0140 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmxM.07.0900 ⚠
protein kinase, putative, serine/threonine ki
— OG7
LmxM.21.0040 ⚠
hypothetical protein, conserved
— OG7
LmxM.13.0730 ⚠
ubiquitin-like protein
— OG7
LmxM.18.0020 ⚠
diphosphomevalonate decarboxylase, putative
— OG7
LmxM.22.0810 ⚠
serine/threonine protein kinase sos2, putativ
— OG7
LmxM.36.4500 ⚠
Protein of unknown function (DUF2870), putati
— OG7
LmxM.33.0210 ⚠
CS domain containing protein, putative
— OG7
LmxM.28.2070 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
LmxM.08_29.1310 ⚠
carnitine/choline acetyltransferase, putative
— OG7
LmxM.08_29.2020 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
LmxM.31.2070 ⚠
cytidylyltransferase, putative
— OG7
LmxM.11.0210 ⚠
acidocalcisomal pyrophosphatase
— OG7
LmxM.33.3970 ⚠
AP-1 adapter complex gamma subunit, putative
— OG7
LmxM.30.1610 ⚠
diphthine synthase-like protein
— OG7
LmxM.24.0210 ⚠
transcription elongation factor, putative
— OG7
LmxM.27.1250 ⚠
Serine-threonine kinase receptor-associated p
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.