LmxM.17.1150

5'-3' exoribonuclease B, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_156818 OG7: OG7_0003221 187 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 187 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.29.1090 ⚠
WW domain containing protein, putative
— OG7
LmxM.28.2070 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
LmxM.08_29.1310 ⚠
carnitine/choline acetyltransferase, putative
— OG7
LmxM.08_29.2020 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
LmxM.31.2070 ⚠
cytidylyltransferase, putative
— OG7
LmxM.11.0210 ⚠
acidocalcisomal pyrophosphatase
— OG7
LmxM.33.3970 ⚠
AP-1 adapter complex gamma subunit, putative
— OG7
LmxM.30.1610 ⚠
diphthine synthase-like protein
— OG7
LmxM.22.0810 ⚠
serine/threonine protein kinase sos2, putativ
— OG7
LmxM.21.0150 ⚠
serine/threonine-protein kinase-like protein
— OG7
LmxM.18.0990 ⚠
UTP-glucose-1-phosphate uridylyltransferase 2
— OG7
LmxM.21.0030 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.1580 ⚠
phosphomannose isomerase, putative
— OG7
LmxM.16.1490 ⚠
hypothetical protein, conserved
— OG7
LmxM.22.0110 ⚠
GMP synthase [glutamine-hydrolysing]
— OG7
LmxM.16.1340 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmxM.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmxM.33.3940 ⚠
target of rapamycin kinase 3, putative
— OG7
LmxM.02.0120 ⚠
phosphatidylinositol 3-kinase-like protein
— OG7
LmxM.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmxM.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LmxM.33.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LmxM.08_29.1180 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.3970 ⚠
cAMP response protein 1, putative
— OG7
LmxM.03.0270 ⚠
FYVE zinc finger/Apolipoprotein A1/A4/E domai
— OG7
LmxM.14.0790 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.0310 ⚠
intraflagellar transport protein 140, putativ
— OG7
LmxM.32.0280 ⚠
hypothetical protein, conserved
— OG7
LmxM.13.1470 ⚠
HECT E3 ligase, putative
— OG7
LmxM.32.1490 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.1510 ⚠
hypothetical protein, conserved
— OG7
LmxM.25.1840 ⚠
General negative regulator of transcription s
— OG7
LmxM.23.0900 ⚠
hypothetical protein, conserved
— OG7
LmxM.21.0800 ⚠
CCR4-NOT transcription complex subunit 1
— OG7
LmxM.34.5390 ⚠
HECT E3 ligase, putative
— OG7
LmxM.29.0490 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.3510 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LmxM.29.0050 ⚠
MATH domain containing protein, putative
— OG7
LmxM.21.1566 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LmxM.32.1180 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LmxM.21.1330partial ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LmxM.05.0400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LmxM.12.0110 ⚠
hypothetical protein, conserved
— OG7
LmxM.07.0280 ⚠
HECT E3 ligase, putative
— OG7
LmxM.16.1550 ⚠
Component of motile flagella 6, putative
— OG7
LmxM.07.0120 ⚠
Sec7 domain containing protein, putative
— OG7
LmxM.10.0950 ⚠
translation initiation factor eif-2b beta sub
— OG7
LmxM.19.1010 ⚠
WD domain, G-beta repeat, putative
— OG7
LmxM.27.1210 ⚠
translation initiation factor eIF2B delta sub
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.