LmxM.22.0110

GMP synthase [glutamine-hydrolysing]
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_100862 OG7: OG7_0002018 178 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 178 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.28.1350 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmxM.08_29.0780 ⚠
U-box domain protein, putative
— Both
LmxM.34.4470 ⚠
Co-chaperone protein P23
— Both
LmxM.27.1620 ⚠
Eukaryotic translation initiation factor 4E-1
— Both
LmxM.26.2370
HECT E3 ligase, putative
— Both
LmxM.31.3680 ⚠
enoyl-CoA hydratase/isomerase family protein,
— Both
LmxM.33.0540
Gamma-soluble NSF attachment protein (SNAP-ga
— Both
LmxM.31.1100
exportin 1, putative
— Both
LmxM.28.1140
electron-transfer-flavoprotein, alpha polypep
— Both
LmxM.25.2130 ⚠
succinyl-CoA synthetase alpha subunit, putati
— Both
LmxM.08_29.2100 ⚠
Present in the outer mitochondrial membrane p
— Both
LmxM.34.0020 ⚠
pyruvate kinase
— Both
LmxM.31.2400
hypothetical protein, conserved
— Both
LmxM.28.2240
hd phosphohydrolase family protein
— Both
LmxM.31.0910
Alpha/beta hydrolase family, putative
— Both
LmxM.28.0060
hypothetical protein, conserved
— Both
LmxM.25.2020
hypothetical protein, conserved
— Both
LmxM.34.1250 ⚠
thioredoxin-like protein
— Both
LmxM.34.0820 ⚠
aspartate aminotransferase, putative
— Both
LmxM.29.3410 ⚠
hypothetical protein, conserved
— Both
LmxM.08.0290 ⚠
iron superoxide dismutase A, mitochondrial
— Both
LmxM.14.1190
Bifunctional NAD(P)H-hydrate repair enzyme
— Both
LmxM.16.0580
dihydroorotase, putative
— Both
LmxM.16.0760
transaldolase, putative
— Both
LmxM.27.2032 ⚠
branched-chain amino acid aminotransferase, p
— Both
LmxM.27.2031 ⚠
branched-chain amino acid aminotransferase, p
— Both
LmxM.27.2030 ⚠
branched-chain amino acid aminotransferase, p
— Both
LmxM.23.1480
alanine racemase, putative
— Both
LmxM.07.0805
N-acetylglucosamine-phosphate mutase, putativ
— Both
LmxM.32.2810 ⚠
transcription elongation factor-like protein
— Both
LmxM.34.0360
enoyl-CoA hydratase/isomerase family protein,
— Both
LmxM.27.2330 ⚠
GTP binding protein, putative
— Both
LmxM.08.0870
hypothetical protein, unknown function
— OG7
LmxM.31.3110 ⚠
Serine hydrolase (FSH1)/50S ribosome-binding
— OG7
LmxM.27.1830 ⚠
GTP binding protein, putative
— OG7
LmxM.22.1690c ⚠
hypothetical protein
— OG7
LmxM.22.1690partial ⚠
hypothetical protein
— OG7
LmxM.22.1690a ⚠
hypothetical protein
— OG7
LmxM.19.1690 ⚠
hypothetical protein
— OG7
LmxM.22.1690b ⚠
hypothetical protein
— OG7
LmxM.32.1710 ⚠
protein kinase, putative
— OG7
LmxM.13.0130 ⚠
Kinesin-13 2
— OG7
LmxM.34.3500 ⚠
zinc finger protein, putative
— OG7
LmxM.01.0210 ⚠
CUE domain/Domain of unknown function (DUF177
— OG7
LmxM.32.2150 ⚠
hypothetical protein, conserved
— OG7
LmxM.28.1380 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmxM.22.0340 ⚠
methylenetetrahydrofolate dehydrogenase-like
— OG7
LmxM.30.2880 ⚠
aldehyde reductase, putative
— OG7
LmxM.28.2500 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LmxM.34.4280 ⚠
Spindle assembly abnormal protein 6 homolog
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.