LmxM.05.0400

structural maintenance of chromosome (SMC), putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_101492 OG7: OG7_0001761 211 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 211 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmxM.08.1090 ⚠
histone deacetylase, putative
— OG7
LmxM.34.2490 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.1270 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.4290 ⚠
nucleolar protein family a, putative
— OG7
LmxM.16.1350 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LmxM.26.1420 ⚠
FYVE zinc finger, putative
— OG7
LmxM.32.2070 ⚠
mitogen-activated protein kinase, putative
— OG7
LmxM.31.0250 ⚠
hypothetical protein, conserved
— OG7
LmxM.21.1670 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.2410 ⚠
ubiquitin hydrolase, putative,cysteine peptid
— OG7
LmxM.23.0120 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmxM.10.0800 ⚠
hypothetical protein, conserved
— OG7
LmxM.08.0510 ⚠
ribose-phosphate pyrophosphokinase, putative
— OG7
LmxM.21.1250 ⚠
adenylate kinase, putative
— OG7
LmxM.30.2970 ⚠
acetyl-CoA carboxylase
— OG7
LmxM.33.3460 ⚠
hypothetical protein, conserved
— OG7
LmxM.06.0500 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmxM.14.1170 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.4090 ⚠
GRIP domain containing protein, putative
— OG7
LmxM.28.2760 ⚠
gamma-tubulin complex component 3
— OG7
LmxM.31.0720 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.1360 ⚠
adenylate kinase, putative
— OG7
LmxM.27.2480 ⚠
hypothetical protein, conserved, WD-repeat pr
— OG7
LmxM.36.2410 ⚠
Cullin protein neddylation domain containing
— OG7
LmxM.29.0660 ⚠
pdz domain containing protein, putative
— OG7
LmxM.33.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LmxM.23.0020 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.5240 ⚠
glycosyl hydrolase, putative
— OG7
LmxM.13.1470 ⚠
HECT E3 ligase, putative
— OG7
LmxM.28.2110 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmxM.24.2290 ⚠
cullin-like protein-like protein
— OG7
LmxM.36.1000 ⚠
intraflagellar transport protein 122, putativ
— OG7
LmxM.16.0020 ⚠
AAA domain containing protein, putative
— OG7
LmxM.24.1060 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— OG7
LmxM.28.1460 ⚠
Cell division control protein 48, putative
— OG7
LmxM.21.1870 ⚠
histone deacetylase, putative
— OG7
LmxM.30.0160 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LmxM.24.1660 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmxM.27.0820 ⚠
parallel beta-helix repeat, putative
— OG7
LmxM.29.2210 ⚠
endosomal trafficking protein RME-8, putative
— OG7
LmxM.26.1260 ⚠
hypothetical protein, unknown function
— OG7
LmxM.15.0700 ⚠
hypothetical protein, conserved
— OG7
LmxM.14.0570 ⚠
WD domain, G-beta repeat, putative
— OG7
LmxM.16.1550 ⚠
Component of motile flagella 6, putative
— OG7
LmxM.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmxM.32.1180 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LmxM.08.0420 ⚠
hypothetical protein,conserved
— OG7
LmxM.32.1930 ⚠
phosphoribosyl transferase, putative, phospho
— OG7
LmxM.10.0130 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.