LmxM.21.1250

adenylate kinase, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_104102 OG7: OG7_0001354 125 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 125 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmxM.14.0570 ⚠
WD domain, G-beta repeat, putative
— Both
LmxM.15.0700 ⚠
hypothetical protein, conserved
— Both
LmxM.08.0510 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
LmxM.21.1440 ⚠
cytochrome b5-like Heme/Steroid binding domai
— Both
LmxM.10.0060 ⚠
thymidylate kinase-like protein
— Both
LmxM.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— Both
LmxM.18.0820 ⚠
hypothetical protein, conserved
— Both
LmxM.36.1450 ⚠
hypothetical protein, conserved
— Both
LmxM.25.2110 ⚠
KIF-1 binding protein C terminal, putative
— Both
LmxM.25.2380 ⚠
glutathionylspermidine synthase, putative
— Both
LmxM.24.1110 ⚠
formin-like protein
— OG7
LmxM.17.0930 ⚠
formin, putative
— OG7
LmxM.08.1130 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LmxM.36.5390 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LmxM.32.1930 ⚠
phosphoribosyl transferase, putative, phospho
— OG7
LmxM.32.2830 ⚠
D-alanyl-glycyl endopeptidase-like protein, p
— OG7
LmxM.27.1870 ⚠
trypanothione synthetase
— OG7
LmxM.32.2850 ⚠
D-alanyl-glycyl endopeptidase-like protein, p
— OG7
LmxM.23.0460 ⚠
trypanothione synthetase, putative
— OG7
LmxM.30.2610 ⚠
RNA polymerase ii largest subunit
— OG7
LmxM.33.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LmxM.02.0120 ⚠
phosphatidylinositol 3-kinase-like protein
— OG7
LmxM.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmxM.33.3940 ⚠
target of rapamycin kinase 3, putative
— OG7
LmxM.34.3500 ⚠
zinc finger protein, putative
— OG7
LmxM.20.0010 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LmxM.28.2110 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmxM.24.2290 ⚠
cullin-like protein-like protein
— OG7
LmxM.30.0160 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LmxM.24.1660 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmxM.34.5390 ⚠
HECT E3 ligase, putative
— OG7
LmxM.16.1220 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmxM.19.0800 ⚠
ABC transporter, putative
— OG7
LmxM.32.0310 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LmxM.05.0400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LmxM.21.1330partial ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LmxM.34.3510 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LmxM.27.1270 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmxM.34.2410 ⚠
ubiquitin hydrolase, putative,cysteine peptid
— OG7
LmxM.31.2910 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.08_29.0140 ⚠
DNA-directed RNA polymerase II subunit 3, put
— OG7
LmxM.23.1380 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LmxM.31.1400 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
LmxM.18.0600 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LmxM.36.6770 ⚠
beta adaptin, putative
— OG7
LmxM.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmxM.36.1720 ⚠
hypothetical protein, conserved
— OG7
LmxM.06.0500 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmxM.14.1170 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.