LmxM.08.0010

adaptor complex protein (AP) 3 delta subunit 1, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_101525 OG7: OG7_0001761 206 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 206 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.33.1510 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LmxM.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmxM.26.1260 ⚠
hypothetical protein, unknown function
— OG7
LmxM.16.1550 ⚠
Component of motile flagella 6, putative
— OG7
LmxM.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmxM.32.1180 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LmxM.29.2210 ⚠
endosomal trafficking protein RME-8, putative
— OG7
LmxM.21.1566 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LmxM.29.0050 ⚠
MATH domain containing protein, putative
— OG7
LmxM.05.0400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LmxM.21.1330partial ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LmxM.27.0380 ⚠
Nuclear pore complex protein 158
— OG7
LmxM.29.0490 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.2610 ⚠
RNA polymerase ii largest subunit
— OG7
LmxM.21.0800 ⚠
CCR4-NOT transcription complex subunit 1
— OG7
LmxM.32.1930 ⚠
phosphoribosyl transferase, putative, phospho
— OG7
LmxM.23.0020 ⚠
hypothetical protein, conserved
— OG7
LmxM.23.0900 ⚠
hypothetical protein, conserved
— OG7
LmxM.24.1660 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmxM.30.0160 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LmxM.16.0020 ⚠
AAA domain containing protein, putative
— OG7
LmxM.25.1840 ⚠
General negative regulator of transcription s
— OG7
LmxM.36.1000 ⚠
intraflagellar transport protein 122, putativ
— OG7
LmxM.24.2290 ⚠
cullin-like protein-like protein
— OG7
LmxM.28.2110 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmxM.06.0260 ⚠
5'-3' exoribonuclease A, putative
— OG7
LmxM.03.0790 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.3070 ⚠
fibrillarin
— OG7
LmxM.19.0100 ⚠
fibrillarin, putative
— OG7
LmxM.31.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— +2 more OG7
LmxM.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— +2 more OG7
LmxM.33.3940 ⚠
target of rapamycin kinase 3, putative
— +2 more OG7
LmxM.02.0120 ⚠
phosphatidylinositol 3-kinase-like protein
— +2 more OG7
LmxM.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— +2 more OG7
LmxM.33.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— +2 more OG7
LmxM.03.0270 ⚠
FYVE zinc finger/Apolipoprotein A1/A4/E domai
— OG7
LmxM.12.0110 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.1790 ⚠
5'-3' exoribonuclease D, putative
— OG7
LmxM.31.3970 ⚠
cAMP response protein 1, putative
— OG7
LmxM.32.1490 ⚠
hypothetical protein, conserved
— OG7
LmxM.13.1470 ⚠
HECT E3 ligase, putative
— OG7
LmxM.32.0280 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.0310 ⚠
intraflagellar transport protein 140, putativ
— OG7
LmxM.14.0790 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.1360 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LmxM.20.0010 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LmxM.17.1150 ⚠
5'-3' exoribonuclease B, putative
— OG7
LmxM.34.3500 ⚠
zinc finger protein, putative
— OG7
LmxM.29.0660 ⚠
pdz domain containing protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.