LmxM.20.0010

DNA-directed RNA polymerase III, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_100190 OG7: OG7_0001821 186 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 186 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.08_29.1830 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LmxM.16.1350 ⚠
DNA-directed rna polymerase I largest subunit
— +1 more OG7
LmxM.30.2640 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— OG7
LmxM.04.0120 ⚠
exosome complex exonuclease RRP40, putative
— OG7
LmxM.30.2650 ⚠
acetoin dehydrogenase e3 component-like prote
— Both
LmxM.27.1550 ⚠
DNA-directed RNA polymerase II-like protein
— Both
LmxM.30.2610 ⚠
RNA polymerase ii largest subunit
— +4 more Both
LmxM.33.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— +4 more Both
LmxM.08_29.0140 ⚠
DNA-directed RNA polymerase II subunit 3, put
— Both
LmxM.28.2060 ⚠
DNA-directed RNA polymerase-like protein
— +1 more Both
LmxM.23.1770 ⚠
exosome component CSL4, putative
— OG7
LmxM.19.0660 ⚠
DNA-directed RNA polymerases I and III subuni
— Both
LmxM.28.2780 ⚠
heat-shock protein hsp70, putative
— OG7
LmxM.22.1580 ⚠
exosome complex exonuclease RRP45 homolog, pu
— OG7
LmxM.18.0370 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LmxM.34.4930 ⚠
tubulin tyrosine ligase, putative
— OG7
LmxM.20.0790 ⚠
tubulin-tyrosine ligase, putative
— OG7
LmxM.11.0400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LmxM.27.2490 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.08_29.1730 ⚠
histone H2A, putative
— OG7
LmxM.18.1370 ⚠
heat shock protein, putative
— OG7
LmxM.08_29.1740 ⚠
histone H2A, putative
— OG7
LmxM.26.0480 ⚠
hypothetical protein, conserved
— OG7
LmxM.17.0280 ⚠
histone H2A variant Z
— OG7
LmxM.01.0640 ⚠
HSP70-like protein
— OG7
LmxM.28.1200 ⚠
luminal binding protein 1 (BiP), putative
— OG7
LmxM.25.1390 ⚠
hypothetical protein, conserved
— OG7
LmxM.14.0010 ⚠
ribosomal RNA processing protein 4, putative,
— OG7
LmxM.25.1270 ⚠
hypothetical protein, conserved
— OG7
LmxM.08_29.1720 ⚠
histone H2A, putative
— OG7
LmxM.34.4710 ⚠
Hsp70 protein, putative
— OG7
LmxM.26.0900 ⚠
chaperone protein-like protein, heat shock 70
— OG7
LmxM.36.5390 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LmxM.15.0700 ⚠
hypothetical protein, conserved
— OG7
LmxM.19.0950 ⚠
hypothetical protein, conserved
— OG7
LmxM.17.0930 ⚠
formin, putative
— OG7
LmxM.02.0320 ⚠
ribosomal RNA processing protein 41B, putativ
— OG7
LmxM.08.1130 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LmxM.24.1110 ⚠
formin-like protein
— OG7
LmxM.36.4895 ⚠
exosome-associated protein 4, putative
— OG7
LmxM.19.0420 ⚠
DNA-directed RNA polymerase III subunit C11,
— OG7
LmxM.36.3020 ⚠
Ribosomal RNA processing protein 41A
— OG7
LmxM.36.4145 ⚠
transcription factor S-II-like protein
— OG7
LmxM.11.0260 ⚠
hypothetical protein, conserved
— OG7
LmxM.26.1240 ⚠
heat shock protein 70-related protein
— OG7
LmxM.28.2770 ⚠
heat-shock protein hsp70, putative
— OG7
LmxM.22.1630 ⚠
ccr4-not transcription complex subunit
— OG7
LmxM.24.2100 ⚠
hypothetical protein, conserved
— OG7
LmxM.10.0800 ⚠
hypothetical protein, conserved
— OG7
LmxM.07.0380 ⚠
RAVE protein 1 C terminal, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.