LmxM.08_29.0140

DNA-directed RNA polymerase II subunit 3, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_101363 OG7: OG7_0003550 107 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 107 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.29.1270 ⚠
hypothetical protein, conserved
— Both
LmxM.16.1350 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LmxM.25.0620 ⚠
RNA polymerase I second largest subunit, puta
— OG7
LmxM.33.2790 ⚠
hypothetical protein, conserved
— Both
LmxM.27.1550 ⚠
DNA-directed RNA polymerase II-like protein
— Both
LmxM.30.2610 ⚠
RNA polymerase ii largest subunit
— +1 more Both
LmxM.30.0160 ⚠
DNA-directed RNA polymerase II subunit 2, put
— Both
LmxM.20.0010 ⚠
DNA-directed RNA polymerase III, putative
— Both
LmxM.33.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— +1 more Both
LmxM.28.2060 ⚠
DNA-directed RNA polymerase-like protein
— Both
LmxM.19.0630 ⚠
histone H3 variant V
— OG7
LmxM.21.1250 ⚠
adenylate kinase, putative
— OG7
LmxM.29.1090 ⚠
WW domain containing protein, putative
— OG7
LmxM.30.2970 ⚠
acetyl-CoA carboxylase
— OG7
LmxM.33.3460 ⚠
hypothetical protein, conserved
— OG7
LmxM.32.2070 ⚠
mitogen-activated protein kinase, putative
— OG7
LmxM.26.1420 ⚠
FYVE zinc finger, putative
— OG7
LmxM.03.0160 ⚠
ABC transporter protein, putative
— OG7
LmxM.29.0910 ⚠
HECT E3 ligase, putative
— OG7
LmxM.36.5700 ⚠
hypothetical protein, conserved
— OG7
LmxM.25.0715 ⚠
hypothetical protein, conserved
— Both
LmxM.34.4260 ⚠
hypothetical protein, conserved
— OG7
LmxM.23.0547 ⚠
hypothetical protein, conserved
— OG7
LmxM.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmxM.34.2250 ⚠
hypothetical protein, conserved
— OG7
LmxM.32.1110 ⚠
hypothetical protein, conserved
— OG7
LmxM.18.0600 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LmxM.04.0960 ⚠
adenylate kinase, putative
— OG7
LmxM.36.2240 ⚠
Gamma-tubulin complex component 3-like protei
— OG7
LmxM.11.0370 ⚠
hypothetical protein, conserved
— OG7
LmxM.10.0870 ⚠
histone H3
— OG7
LmxM.16.0570 ⚠
histone H3
— OG7
LmxM.16.0600 ⚠
histone H3, putative
— OG7
LmxM.16.0575 ⚠
histone H3
— OG7
LmxM.27.1270 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmxM.08_29.1740 ⚠
histone H2A, putative
— OG7
LmxM.08_29.1730 ⚠
histone H2A, putative
— OG7
LmxM.13.1070 ⚠
hypothetical protein, unknown function
— OG7
LmxM.08_29.1720 ⚠
histone H2A, putative
— OG7
LmxM.21.0920 ⚠
histone H2A, putative
— OG7
LmxM.18.0820 ⚠
hypothetical protein, conserved
— OG7
LmxM.09.1060 ⚠
DNA-directed RNA polymerase III subunit, puta
— OG7
LmxM.05.0400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LmxM.21.1330partial ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LmxM.34.3510 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LmxM.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LmxM.16.0610 ⚠
histone H3, putative
— OG7
LmxM.19.0800 ⚠
ABC transporter, putative
— OG7
LmxM.18.0790 ⚠
DNA-directed RNA polymerase I subunit RPB5z,
— OG7
LmxM.32.0310 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.