LmxM.18.0600

Zn-finger in Ran binding protein and others/FYVE zinc finger, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_139898 OG7: OG7_0001169 250 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 250 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmxM.34.5390 ⚠
HECT E3 ligase, putative
— OG7
LmxM.07.0280 ⚠
HECT E3 ligase, putative
— OG7
LmxM.29.0910 ⚠
HECT E3 ligase, putative
— Both
LmxM.29.1090 ⚠
WW domain containing protein, putative
— OG7
LmxM.11.0890 ⚠
hypothetical protein, conserved
— Both
LmxM.11.0370 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LmxM.32.2070 ⚠
mitogen-activated protein kinase, putative
— OG7
LmxM.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LmxM.33.3460 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.2970 ⚠
acetyl-CoA carboxylase
— OG7
LmxM.06.0500 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmxM.33.4090 ⚠
GRIP domain containing protein, putative
— OG7
LmxM.31.0720 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.4030 ⚠
geranylgeranyltransferase, putative
— OG7
LmxM.29.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmxM.05.0890 ⚠
CPSF A subunit region, putative
— OG7
LmxM.02.0120 ⚠
phosphatidylinositol 3-kinase-like protein
— OG7
LmxM.29.3710 ⚠
CPSF-domain protein, putative
— OG7
LmxM.08_29.0600 ⚠
hypothetical protein, conserved
— OG7
LmxM.27.0820 ⚠
parallel beta-helix repeat, putative
— OG7
LmxM.24.1660 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmxM.36.2850 ⚠
hypothetical protein, conserved
— OG7
LmxM.28.1460 ⚠
Cell division control protein 48, putative
— OG7
LmxM.36.5240 ⚠
glycosyl hydrolase, putative
— OG7
LmxM.30.0310 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LmxM.31.2650 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmxM.33.3940 ⚠
target of rapamycin kinase 3, putative
— OG7
LmxM.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmxM.29.3410 ⚠
hypothetical protein, conserved
— OG7
LmxM.32.2150 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.1360 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LmxM.31.1330 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LmxM.09.1300 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LmxM.24.0650 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LmxM.10.0130 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.4500 ⚠
Protein of unknown function (DUF2870), putati
— OG7
LmxM.16.1490 ⚠
hypothetical protein, conserved
— OG7
LmxM.22.0110 ⚠
GMP synthase [glutamine-hydrolysing]
— OG7
LmxM.21.1870 ⚠
histone deacetylase, putative
— OG7
LmxM.10.0690 ⚠
hypothetical protein, conserved
— OG7
LmxM.08.0420 ⚠
hypothetical protein,conserved
— OG7
LmxM.32.2780 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmxM.08.1090 ⚠
histone deacetylase, putative
— OG7
LmxM.30.2610 ⚠
RNA polymerase ii largest subunit
— OG7
LmxM.04.0960 ⚠
adenylate kinase, putative
— OG7
LmxM.18.0830 ⚠
Periodic tryptophan protein 2 homolog, putati
— OG7
LmxM.31.1400 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.