LmxM.18.0830

Periodic tryptophan protein 2 homolog, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_102497 OG7: OG7_0007331 139 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 139 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.36.4210
WD domain, G-beta repeat/Utp21 specific WD40
— Both
LmxM.14.0570
WD domain, G-beta repeat, putative
— Both
LmxM.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmxM.15.0700
hypothetical protein, conserved
— Both
LmxM.08.0510 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
LmxM.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— Both
LmxM.18.0820
hypothetical protein, conserved
— Both
LmxM.16.0380 ⚠
tubulin tyrosine ligase, putative
— Both
LmxM.08.1130 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LmxM.36.5390 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LmxM.32.1930 ⚠
phosphoribosyl transferase, putative, phospho
— OG7
LmxM.27.2490 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.11.0400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LmxM.20.0790 ⚠
tubulin-tyrosine ligase, putative
— OG7
LmxM.34.4930 ⚠
tubulin tyrosine ligase, putative
— OG7
LmxM.18.0370 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LmxM.08_29.0260 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LmxM.31.2930 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.29.2280 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.30.2610 ⚠
RNA polymerase ii largest subunit
— OG7
LmxM.33.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LmxM.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmxM.34.3500 ⚠
zinc finger protein, putative
— OG7
LmxM.20.0010 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LmxM.09.0891 ⚠
polyubiquitin, putative
— OG7
LmxM.31.1360 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LmxM.24.0910 ⚠
minchromosome maintenance (MCM) complex subun
— OG7
LmxM.08_29.1830 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LmxM.28.2110 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmxM.24.2290 ⚠
cullin-like protein-like protein
— OG7
LmxM.16.0020 ⚠
AAA domain containing protein, putative
— OG7
LmxM.17.0930 ⚠
formin, putative
— OG7
LmxM.30.0160 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LmxM.24.1660 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmxM.31.2960 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
LmxM.02.0120 ⚠
phosphatidylinositol 3-kinase-like protein
— OG7
LmxM.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmxM.36.3530partial ⚠
polyubiquitin, putative
— OG7
LmxM.36.0600 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LmxM.34.4260 ⚠
hypothetical protein, conserved
— OG7
LmxM.16.1220 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmxM.32.2700 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
LmxM.36.1720 ⚠
hypothetical protein, conserved
— OG7
LmxM.09.0250 ⚠
DNA replication licensing factor MCM4
— OG7
LmxM.36.6770 ⚠
beta adaptin, putative
— OG7
LmxM.18.0600 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LmxM.21.1330partial ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LmxM.34.3510 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LmxM.23.1380 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LmxM.05.0400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.