LmxM.16.0380

tubulin tyrosine ligase, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_104876 OG7: OG7_0001164 146 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 146 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.16.1270 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.0160 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LmxM.24.1660 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmxM.22.1130 ⚠
Beta-lactamase superfamily domain containing
— OG7
LmxM.26.2080 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.2610 ⚠
RNA polymerase ii largest subunit
— OG7
LmxM.27.0860 ⚠
WD domain, G-beta repeat, putative
— OG7
LmxM.36.0470 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LmxM.31.2960 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
LmxM.21.0950 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LmxM.18.1490 ⚠
chaperone protein DnaJ, putative
— OG7
LmxM.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmxM.02.0120 ⚠
phosphatidylinositol 3-kinase-like protein
— OG7
LmxM.04.1170 ⚠
Double RNA binding domain protein 3
— OG7
LmxM.30.2650 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LmxM.33.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LmxM.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmxM.36.2410 ⚠
Cullin protein neddylation domain containing
— OG7
LmxM.32.1610 ⚠
cytosolic nonspecific dipeptidase, putative
— OG7
LmxM.06.0500 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmxM.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LmxM.23.0550 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LmxM.33.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LmxM.28.1820 ⚠
Replication factor A protein 1
— OG7
LmxM.30.1900 ⚠
ubiquitin-fusion protein
— OG7
LmxM.28.2385 ⚠
DNA replication licensing factor, putative
— OG7
LmxM.32.2690 ⚠
DNAJ family-like protein
— OG7
LmxM.31.0850 ⚠
polypyrimidine tract-binding protein, putativ
— OG7
LmxM.28.1900 ⚠
DnaJ domain containing protein, putative
— OG7
LmxM.31.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmxM.30.2030 ⚠
ubiquitin-fusion protein
— OG7
LmxM.36.3060 ⚠
cullin-like protein
— OG7
LmxM.32.3050 ⚠
tyrosyl-DNA phosphodiesterase-like protein
— OG7
LmxM.34.4910 ⚠
DNA replication factor, putative
— OG7
LmxM.28.1270 ⚠
DnaJ domain containing protein, putative
— OG7
LmxM.31.1940 ⚠
DnaJ homolog, putative
— OG7
LmxM.14.1270 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LmxM.08.0650 ⚠
DnaJ domain containing protein, putative
— OG7
LmxM.33.1140 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmxM.36.6770 ⚠
beta adaptin, putative
— OG7
LmxM.28.2010 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.3530partial ⚠
polyubiquitin, putative
— OG7
LmxM.30.1890 ⚠
peptidase m20/m25/m40 family-like protein
— OG7
LmxM.05.0330 ⚠
DNA replication licensing factor, putative, m
— OG7
LmxM.22.1120 ⚠
Beta-lactamase superfamily domain containing
— OG7
LmxM.29.3440 ⚠
DNA ligase I, putative
— OG7
LmxM.07.1030 ⚠
PPIase, putative, peptidyl-prolyl cis-trans i
— OG7
LmxM.15.1170 ⚠
hypothetical protein, conserved
— OG7
LmxM.03.0610 ⚠
kinase-like protein
— OG7
LmxM.07.0100 ⚠
pitrilysin-like metalloprotease, metallo-pept
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.