LmxM.29.3440

DNA ligase I, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_100906 OG7: OG7_0002598 157 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 157 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.17.0350 ⚠
dihydrouridine synthase (Dus), putative
— Both
LmxM.33.1140 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmxM.30.1930 ⚠
dihydrouridine synthase (Dus), putative
— Both
LmxM.03.0770
Ubiquitin-like domain containing protein, put
— Both
LmxM.36.0470 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LmxM.34.4930 ⚠
tubulin tyrosine ligase, putative
— OG7
LmxM.34.4550
hypothetical protein, conserved
— Both
LmxM.08_29.2110
UDP-glucose:glycoprotein glucosyltransferase,
— Both
LmxM.34.1050
protein kinase, putative
— OG6
LmxM.20.0250 ⚠
deoxyhypusine synthase, putative
— Both
LmxM.36.5620
isoleucyl-tRNA synthetase, putative
— Both
LmxM.25.1450
Peptide chain release factor 1, mitochondrial
— Both
LmxM.25.0170 ⚠
cleavage and polyadenylation specificity fact
— Both
LmxM.20.1710
tRNA (Uracil-5-)-methyltransferase, putative
— Both
LmxM.27.0380
Nuclear pore complex protein 158
— Both
LmxM.34.0190 ⚠
NLI interacting factor-like phosphatase, puta
— Both
LmxM.28.2220
2,3-bisphosphoglycerate-independent phosphogl
— Both
LmxM.21.0810
methionyl-tRNA synthetase, putative
— Both
LmxM.29.3300
UV excision repair RAD23-like protein
— Both
LmxM.18.0010 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
LmxM.22.1240 ⚠
translation initiation factor IF-2, putative
— Both
LmxM.05.0820
hypothetical protein, conserved
— Both
LmxM.23.1470
hypothetical protein, conserved
— Both
LmxM.02.0360
casein kinase II, alpha chain, putative
— OG6
LmxM.22.1540
alanyl-tRNA synthetase, putative
— Both
LmxM.28.0450 ⚠
DIS3-like exonuclease, putative
— Both
LmxM.21.0950 ⚠
Programmed cell death protein 2, C-terminal p
— Both
LmxM.28.1820
Replication factor A protein 1
— Both
LmxM.22.1120 ⚠
Beta-lactamase superfamily domain containing
— Both
LmxM.22.1130 ⚠
Beta-lactamase superfamily domain containing
— Both
LmxM.31.3980
Gar1/Naf1 RNA binding region, putative
— Both
LmxM.03.0750
TatD related DNase, putative
— Both
LmxM.11.0210 ⚠
acidocalcisomal pyrophosphatase
— Both
LmxM.03.0910 ⚠
inorganic pyrophosphatase, putative
— Both
LmxM.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmxM.28.0330 ⚠
rrp44p homologue, putative
— OG7
LmxM.10.0570 ⚠
zinc-binding dehydrogenase-like protein
— OG7
LmxM.26.2080 ⚠
hypothetical protein, conserved
— OG7
LmxM.27.2490 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.12.0060 ⚠
ribonuclease mar1
— OG7
LmxM.11.0400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LmxM.08.0310 ⚠
Isochorismatase family, putative
— OG7
LmxM.17.1130 ⚠
NOL1/NOP2/sun family, putative
— OG7
LmxM.18.1110 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LmxM.08_29.2400 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LmxM.16.1130 ⚠
tyrosyl or methionyl-tRNA synthetase-like pro
— OG7
LmxM.21.0040 ⚠
hypothetical protein, conserved
— OG7
LmxM.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.36.6080 ⚠
rab-like GTPase activating protein, putative
— OG7
LmxM.31.0100 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.