LmxM.18.0010

kinetoplast polyadenylation/uridylation factor 1
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_115819 OG7: OG7_0018045 99 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 99 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.34.1050
protein kinase, putative
— OG6
LmxM.20.0950 ⚠
conserved protein, unknown function
— OG7
LmxM.05.0820 ⚠
hypothetical protein, conserved
— Both
LmxM.21.0810 ⚠
methionyl-tRNA synthetase, putative
— Both
LmxM.27.0380 ⚠
Nuclear pore complex protein 158
— Both
LmxM.29.2320 ⚠
SET domain containing protein, putative
— Both
LmxM.20.1710 ⚠
tRNA (Uracil-5-)-methyltransferase, putative
— Both
LmxM.25.0170 ⚠
cleavage and polyadenylation specificity fact
— Both
LmxM.29.1120 ⚠
importin alpha, putative
— Both
LmxM.36.5620 ⚠
isoleucyl-tRNA synthetase, putative
— Both
LmxM.20.0250 ⚠
deoxyhypusine synthase, putative
— Both
LmxM.29.0610
nitrate reductase, putative
— OG6
LmxM.30.2600 ⚠
calreticulin, putative
— Both
LmxM.08_29.2180 ⚠
Domain of unknown function (DUF4379), putativ
— OG7
LmxM.22.0300 ⚠
hypothetical protein, conserved
— Both
LmxM.26.1000 ⚠
glucosidase II beta subunit-like protein, put
— Both
LmxM.29.2600 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— Both
LmxM.08_29.2110 ⚠
UDP-glucose:glycoprotein glucosyltransferase,
— Both
LmxM.34.4550 ⚠
hypothetical protein, conserved
— Both
LmxM.34.0350 ⚠
hypothetical protein, conserved
— Both
LmxM.17.0350 ⚠
dihydrouridine synthase (Dus), putative
— Both
LmxM.34.2730 ⚠
acyl-CoA dehydrogenase, putative
— Both
LmxM.11.0530 ⚠
hypothetical protein, conserved
— Both
LmxM.08_29.1580 ⚠
XPC-binding domain containing protein, putati
— Both
LmxM.29.0630 ⚠
histidyl-tRNA synthetase, putative
— Both
LmxM.28.0330 ⚠
rrp44p homologue, putative
— OG7
LmxM.20.1730 ⚠
mitochondrial RNA ligase 2
— OG7
LmxM.33.1140 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmxM.32.0310 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LmxM.21.0030 ⚠
hypothetical protein, conserved
— OG7
LmxM.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmxM.18.1110 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LmxM.30.1930 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmxM.16.1130 ⚠
tyrosyl or methionyl-tRNA synthetase-like pro
— OG7
LmxM.21.0040 ⚠
hypothetical protein, conserved
— OG7
LmxM.17.1130 ⚠
NOL1/NOP2/sun family, putative
— OG7
LmxM.03.0160 ⚠
ABC transporter protein, putative
— OG7
LmxM.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.19.0800 ⚠
ABC transporter, putative
— Both
LmxM.24.1340 ⚠
translation initiation factor IF-2, putative
— OG7
LmxM.36.6080 ⚠
rab-like GTPase activating protein, putative
— OG7
LmxM.29.0700 ⚠
NUDC-like protein
— OG7
LmxM.32.1400 ⚠
protein kinase, putative
— OG7
LmxM.33.3430 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmxM.29.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.22.0470 ⚠
Putative tRNA binding domain containing prote
— OG7
LmxM.36.0470 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LmxM.23.0300 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LmxM.36.4100 ⚠
glycosyl hydrolase-like protein
— OG7
LmxM.26.1140 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.