LmxM.36.0470

dihydrouridine synthase domain protein-like protein
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_102617 OG7: OG7_0002064 207 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 207 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.29.3440 ⚠
DNA ligase I, putative
— OG7
LmxM.29.1980 ⚠
C2H2 type zinc-finger (2 copies), putative
— OG7
LmxM.22.0140 ⚠
hypothetical protein, conserved
— OG7
LmxM.18.0010 ⚠
kinetoplast polyadenylation/uridylation facto
— OG7
LmxM.28.1220 ⚠
hypothetical protein, conserved
— OG7
LmxM.26.0630 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.2600 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG7
LmxM.26.1290 ⚠
Cupin-like domain containing protein, putativ
— OG7
LmxM.29.0910 ⚠
HECT E3 ligase, putative
— OG7
LmxM.29.1090 ⚠
WW domain containing protein, putative
— OG7
LmxM.07.0280 ⚠
HECT E3 ligase, putative
— OG7
LmxM.34.5390 ⚠
HECT E3 ligase, putative
— OG7
LmxM.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmxM.08_29.2110 ⚠
UDP-glucose:glycoprotein glucosyltransferase,
— OG7
LmxM.36.2420 ⚠
serine peptidase, Clan SC, Family S9B
— OG7
LmxM.03.0610 ⚠
kinase-like protein
— OG7
LmxM.15.1170 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.4550 ⚠
hypothetical protein, conserved
— OG7
LmxM.07.0100 ⚠
pitrilysin-like metalloprotease, metallo-pept
— OG7
LmxM.24.1170 ⚠
hypothetical protein, conserved
— OG7
LmxM.18.0090 ⚠
alpha glucosidase II subunit, putative
— OG7
LmxM.30.2980 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.4100 ⚠
glycosyl hydrolase-like protein
— OG7
LmxM.03.0910 ⚠
inorganic pyrophosphatase, putative
— OG7
LmxM.11.0210 ⚠
acidocalcisomal pyrophosphatase
— OG7
LmxM.22.0300 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.0630 ⚠
histidyl-tRNA synthetase, putative
— OG7
LmxM.23.1640 ⚠
Galactose oxidase, central domain containing
— OG7
LmxM.08.0300 ⚠
Isochorismatase family, putative
— OG7
LmxM.34.4930 ⚠
tubulin tyrosine ligase, putative
— OG7
LmxM.18.0370 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LmxM.08_29.0260 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LmxM.31.2930 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.29.2280 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.16.0380 ⚠
tubulin tyrosine ligase, putative
— OG7
LmxM.30.2600 ⚠
calreticulin, putative
— OG7
LmxM.05.0970 ⚠
mercaptopyruvate sulfurtransferase
— OG7
LmxM.33.2340 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LmxM.29.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.18.0700 ⚠
HEAT repeats, putative
— OG7
LmxM.27.0860 ⚠
WD domain, G-beta repeat, putative
— OG7
LmxM.17.1450 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LmxM.20.1710 ⚠
tRNA (Uracil-5-)-methyltransferase, putative
— OG7
LmxM.29.2840 ⚠
GTPase activator-like protein
— OG7
LmxM.36.5620 ⚠
isoleucyl-tRNA synthetase, putative
— OG7
LmxM.03.0750 ⚠
TatD related DNase, putative
— OG7
LmxM.25.0870 ⚠
protein kinase, putative
— OG7
LmxM.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.32.1400 ⚠
protein kinase, putative
— OG7
LmxM.34.2950 ⚠
pentatricopeptide repeat domain containing pr
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.