LmxM.08.0300

Isochorismatase family, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_153353 OG7: OG7_0006505 98 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 98 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.27.2490 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.20.0790 ⚠
tubulin-tyrosine ligase, putative
— OG7
LmxM.36.0180 ⚠
elongation factor 2
— OG7
LmxM.10.1140 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LmxM.30.2720 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmxM.30.1930 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmxM.36.4060 ⚠
regulator of chromosome condensation 1-like p
— OG7
LmxM.11.0400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LmxM.32.0200 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LmxM.34.2450 ⚠
HECT E3 ligase, putative
— OG7
LmxM.15.1300 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.10.0560 ⚠
zinc binding dehydrogenase-like protein
— OG7
LmxM.32.3050 ⚠
tyrosyl-DNA phosphodiesterase-like protein
— OG7
LmxM.26.2090 ⚠
hypothetical protein, unknown function
— OG7
LmxM.34.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.09.1210 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LmxM.18.1150 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LmxM.16.0390 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LmxM.28.1220 ⚠
hypothetical protein, conserved
— OG7
LmxM.17.0240 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmxM.26.0740 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmxM.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmxM.28.1820 ⚠
Replication factor A protein 1
— OG7
LmxM.23.0550 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LmxM.21.0660 ⚠
nucleotide-binding protein, putative
— OG7
LmxM.28.2010 ⚠
hypothetical protein, conserved
— OG7
LmxM.05.0230 ⚠
hydrogenase, putative
— OG7
LmxM.03.0610 ⚠
kinase-like protein
— OG7
LmxM.07.0100 ⚠
pitrilysin-like metalloprotease, metallo-pept
— OG7
LmxM.03.0750 ⚠
TatD related DNase, putative
— OG7
LmxM.05.0970 ⚠
mercaptopyruvate sulfurtransferase
— OG7
LmxM.26.0430 ⚠
nucleotide binding protein-like protein
— OG7
LmxM.29.3440 ⚠
DNA ligase I, putative
— OG7
LmxM.22.1120 ⚠
Beta-lactamase superfamily domain containing
— OG7
LmxM.23.1640 ⚠
Galactose oxidase, central domain containing
— OG7
LmxM.30.1890 ⚠
peptidase m20/m25/m40 family-like protein
— OG7
LmxM.05.0790 ⚠
Mitochondrial glycoprotein, putative
— OG7
LmxM.29.2270 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.4060 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.33.1140 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmxM.16.0540 ⚠
aspartate carbamoyltransferase, putative
— OG7
LmxM.29.1980 ⚠
C2H2 type zinc-finger (2 copies), putative
— OG7
LmxM.08_29.1210 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.2020 ⚠
succinyl-diaminopimelate desuccinylase-like p
— OG7
LmxM.29.0970 ⚠
p22 protein precursor, putative
— OG7
LmxM.23.0310 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.4370 ⚠
HECT E3 ligase, putative
— OG7
LmxM.18.1570 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LmxM.33.3550 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LmxM.36.2600 ⚠
cyclin-e binding protein 1-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.