LmxM.28.2010

hypothetical protein, conserved
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_146486 OG7: OG7_0042742 103 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 103 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.17.0240 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmxM.02.0360
casein kinase II, alpha chain, putative
— OG6
LmxM.21.0950 ⚠
Programmed cell death protein 2, C-terminal p
— Both
LmxM.28.1820
Replication factor A protein 1
— Both
LmxM.22.1120 ⚠
Beta-lactamase superfamily domain containing
— Both
LmxM.22.1130 ⚠
Beta-lactamase superfamily domain containing
— Both
LmxM.03.0750
TatD related DNase, putative
— Both
LmxM.10.0570 ⚠
zinc-binding dehydrogenase-like protein
— OG7
LmxM.36.0180 ⚠
elongation factor 2
— OG7
LmxM.31.2200 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
LmxM.26.2080 ⚠
hypothetical protein, conserved
— OG7
LmxM.05.0460 ⚠
GTPase, putative
— OG7
LmxM.32.2400 ⚠
GTPase protein, putative
— OG7
LmxM.26.1370 ⚠
GTP-binding protein-like protein, guanine nuc
— OG7
LmxM.34.5210 ⚠
hypothetical protein, conserved
— OG7
LmxM.17.0350 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmxM.22.1480 ⚠
Mitochondrial glycoprotein, putative
— OG7
LmxM.36.2600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LmxM.33.3960 ⚠
HECT E3 ligase, putative
— OG7
LmxM.31.1090 ⚠
HECT E3 ligase, putative
— OG7
LmxM.36.0470 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LmxM.11.0420 ⚠
regulator of chromatin condensation, putative
— OG7
LmxM.36.4030 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LmxM.29.2270 ⚠
hypothetical protein, conserved
— OG7
LmxM.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmxM.26.0740 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmxM.08.0310 ⚠
Isochorismatase family, putative
— OG7
LmxM.09.1210 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LmxM.18.1570 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LmxM.10.1140 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LmxM.33.3550 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LmxM.16.0390 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LmxM.16.0380 ⚠
tubulin tyrosine ligase, putative
— OG7
LmxM.29.2280 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.31.2930 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.08_29.0260 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LmxM.18.0370 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LmxM.34.4930 ⚠
tubulin tyrosine ligase, putative
— OG7
LmxM.08.0300 ⚠
Isochorismatase family, putative
— OG7
LmxM.23.0310 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.15.1300 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.32.0200 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LmxM.36.4060 ⚠
regulator of chromosome condensation 1-like p
— OG7
LmxM.30.2720 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmxM.36.4370 ⚠
HECT E3 ligase, putative
— OG7
LmxM.27.2490 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.11.0400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LmxM.12.0060 ⚠
ribonuclease mar1
— OG7
LmxM.05.0230
hydrogenase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.