LmxM.33.3960

HECT E3 ligase, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_158358 OG7: OG7_0002947 157 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 157 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.34.3260 ⚠
Peroxin 19
— OG7
LmxM.01.0160 ⚠
LSM domain containing protein, putative
— OG7
LmxM.36.2600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LmxM.33.2020 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmxM.11.0420 ⚠
regulator of chromatin condensation, putative
— OG7
LmxM.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmxM.26.0740 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmxM.17.0240 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmxM.34.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.15.1300 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.33.4060 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.28.1820 ⚠
Replication factor A protein 1
— OG7
LmxM.28.2010 ⚠
hypothetical protein, conserved
— OG7
LmxM.32.0200 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LmxM.08.0320 ⚠
mitochondrial associated ribonuclease, putati
— OG7
LmxM.33.2810 ⚠
Carboxypeptidase-like protein
— OG7
LmxM.36.4030 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LmxM.12.0060 ⚠
ribonuclease mar1
— OG7
LmxM.08.0310 ⚠
Isochorismatase family, putative
— OG7
LmxM.08.0300 ⚠
Isochorismatase family, putative
— OG7
LmxM.05.0970 ⚠
mercaptopyruvate sulfurtransferase
— OG7
LmxM.23.1640 ⚠
Galactose oxidase, central domain containing
— OG7
LmxM.15.1010 ⚠
glutamate dehydrogenase
— OG7
LmxM.27.0940 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LmxM.19.1050 ⚠
hypothetical protein, unknown function
— OG7
LmxM.16.0390 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LmxM.33.2750 ⚠
methyltransferase-like protein
— OG7
LmxM.21.0875 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.4540 ⚠
13 kDa deflagellation-inducible protein, puta
— OG7
LmxM.18.0650 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
LmxM.07.0100 ⚠
pitrilysin-like metalloprotease, metallo-pept
— OG7
LmxM.11.0920 ⚠
Short C-terminal domain/PUB domain containing
— OG7
LmxM.05.0610 ⚠
Surp module, putative
— OG7
LmxM.22.0650 ⚠
guide RNA associated protein, GAP2, putative
— OG7
LmxM.18.0550 ⚠
hypothetical protein, conserved
— OG7
LmxM.32.2260 ⚠
glycosyl hydrolase-like protein
— OG7
LmxM.34.0920 ⚠
hypothetical protein, conserved
— OG7
LmxM.32.2980 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.3200 ⚠
RNA-binding protein, putative
— OG7
LmxM.31.2390 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.0970 ⚠
p22 protein precursor, putative
— OG7
LmxM.08_29.1210 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.0560 ⚠
hypothetical protein, conserved
— OG7
LmxM.22.1480 ⚠
Mitochondrial glycoprotein, putative
— OG7
LmxM.05.0790 ⚠
Mitochondrial glycoprotein, putative
— OG7
LmxM.06.0940 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.1550 ⚠
pseudouridine synthase A-like protein, putati
— OG7
LmxM.03.0450 ⚠
TLD domain protein, conserved
— OG7
LmxM.26.0430 ⚠
nucleotide binding protein-like protein
— OG7
LmxM.36.1955 ⚠
TLD, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.