LmxM.11.0420

regulator of chromatin condensation, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_147368 OG7: OG7_0000958 183 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 183 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.28.2010 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.2810 ⚠
Carboxypeptidase-like protein
— OG7
LmxM.29.0050 ⚠
MATH domain containing protein, putative
— OG7
LmxM.25.0170 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmxM.16.1550 ⚠
Component of motile flagella 6, putative
— OG7
LmxM.34.3260 ⚠
Peroxin 19
— OG7
LmxM.33.4540 ⚠
13 kDa deflagellation-inducible protein, puta
— OG7
LmxM.36.4030 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LmxM.33.2750 ⚠
methyltransferase-like protein
— OG7
LmxM.25.0610 ⚠
Regulatory-associated protein of TOR1
— OG7
LmxM.24.0930 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.1510 ⚠
NLI interacting factor-like phosphatase/Zinc
— OG7
LmxM.08_29.0060 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LmxM.27.1970 ⚠
small nuclear ribonucleoprotein protein, puta
— OG7
LmxM.33.3430 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmxM.18.1100 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmxM.08_29.1100 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmxM.30.2850 ⚠
ribosomal protein l7/l12-like protein
— OG7
LmxM.10.0890 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LmxM.20.0260 ⚠
Midasin, putative
— OG7
LmxM.27.2170 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.1470 ⚠
EAP30/Vps36 family, putative
— OG7
LmxM.28.1760 ⚠
protein kinase, putative
— OG7
LmxM.24.1970 ⚠
Nucleoporin NUP76
— OG7
LmxM.04.0520 ⚠
huntingtin interacting protein (HIP), putativ
— OG7
LmxM.34.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.24.1960 ⚠
hypothetical protein, conserved
— OG7
LmxM.08_29.2210 ⚠
leucine-rich repeat-containing protein
— OG7
LmxM.15.1300 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.31.1340 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmxM.24.0280 ⚠
Dynein intermediate chain 1, axonemal
— OG7
LmxM.34.2450 ⚠
HECT E3 ligase, putative
— OG7
LmxM.32.0200 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LmxM.29.3620 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.4280 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmxM.31.3930 ⚠
HECT E3 ligase, putative
— OG7
LmxM.36.2630 ⚠
protein kinase, putative
— OG7
LmxM.08_29.1240 ⚠
Hsp70 protein/TPR repeat, putative
— OG7
LmxM.30.3110 ⚠
Flagellum attachment zone protein 14
— OG7
LmxM.36.4370 ⚠
HECT E3 ligase, putative
— OG7
LmxM.29.1990 ⚠
cyclosome subunit-like protein
— OG7
LmxM.33.4060 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.36.4040 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.2670 ⚠
ankyrin repeat protein, putative
— OG7
LmxM.26.1220 ⚠
hypothetical protein, conserved
— OG7
LmxM.28.1820 ⚠
Replication factor A protein 1
— OG7
LmxM.15.1200 ⚠
protein kinase, putative
— OG7
LmxM.09.1210 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LmxM.13.0160 ⚠
protein kinase A regulatory subunit
— OG7
LmxM.18.1150 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.