LmxM.31.3930

HECT E3 ligase, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_147203 OG7: OG7_0031172 90 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 90 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.32.0280
hypothetical protein, conserved
— Both
LmxM.33.1390 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LmxM.09.0990 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LmxM.16.1550 ⚠
Component of motile flagella 6, putative
— OG7
LmxM.09.1220
AAA family ATPase, putative
— Both
LmxM.12.0210
proteasome regulatory ATPase subunittcc1l8.3,
— OG6
LmxM.31.2820
proteasome regulatory non-ATP-ase subunit, pu
— Both
LmxM.31.0390
19S proteasome non-atpase subunit 8
— Both
LmxM.08_29.0120
proteasome regulatory non-ATPase subunit, put
— Both
LmxM.34.3950
PRP8 protein homologue, putative, U5 snRNA-as
— Both
LmxM.15.1190 ⚠
cyclic nucleotide-binding domain containing p
— Both
LmxM.17.0800
OSM3-like kinesin, putative
— OG6
LmxM.36.4060 ⚠
regulator of chromosome condensation 1-like p
— OG7
LmxM.27.1460
proteasome regulatory non-ATP-ase subunit 3,
— Both
LmxM.17.0920 ⚠
ATP-dependent RNA helicase, putative
— Both
LmxM.21.0760
proteasome regulatory non-ATP-ase subunit 5,
— Both
LmxM.13.0500 ⚠
ATP-dependent RNA helicase, putative
— Both
LmxM.19.1120
proteasome regulatory non-ATP-ase subunit 9,
— Both
LmxM.07.1120
proteasome regulatory non-ATP-ase subunit, pu
— Both
LmxM.29.1990
cyclosome subunit-like protein
— Both
LmxM.31.2130
RNA recognition motif. (a.k.a. RRM, RBD, or R
— Both
LmxM.31.0310
intraflagellar transport protein 140, putativ
— Both
LmxM.36.4360
Regulatory particle triple-A ATPase subunit 6
— OG6
LmxM.08_29.1100 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmxM.33.4620 ⚠
cyclic nucleotide-binding domain containing p
— OG7
LmxM.23.1380 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LmxM.31.1400 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
LmxM.31.3970 ⚠
cAMP response protein 1, putative
— OG7
LmxM.33.2820 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LmxM.13.0160 ⚠
protein kinase A regulatory subunit
— OG7
LmxM.20.1240 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LmxM.03.0270 ⚠
FYVE zinc finger/Apolipoprotein A1/A4/E domai
— OG7
LmxM.33.3430 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmxM.04.0520 ⚠
huntingtin interacting protein (HIP), putativ
— OG7
LmxM.25.0610 ⚠
Regulatory-associated protein of TOR1
— Both
LmxM.29.3260 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmxM.32.0140 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmxM.03.0480 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LmxM.34.2670 ⚠
ankyrin repeat protein, putative
— OG7
LmxM.33.4280 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmxM.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmxM.11.0420 ⚠
regulator of chromatin condensation, putative
— OG7
LmxM.33.2020 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmxM.36.2600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LmxM.30.2720 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmxM.30.3110
Flagellum attachment zone protein 14
— Both
LmxM.33.0650
proteasome regulatory non-ATPase subunit 11,
— Both
LmxM.04.0550
Intraflagellar transport protein 139, putativ
— Both
LmxM.29.0490
hypothetical protein, conserved
— Both
LmxM.14.0810
kinesin, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.