LmxM.34.3950

PRP8 protein homologue, putative, U5 snRNA-associated splicing factor
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_101765 OG7: OG7_0006744 71 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 71 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.13.0500 ⚠
ATP-dependent RNA helicase, putative
— Both
LmxM.17.0920 ⚠
ATP-dependent RNA helicase, putative
— Both
LmxM.31.1400 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
LmxM.23.1380 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LmxM.31.2490
hypothetical protein, conserved
— Both
LmxM.29.1205 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LmxM.32.3190
small nuclear ribonucleoprotein SmD2
— Both
LmxM.31.3930
HECT E3 ligase, putative
— Both
LmxM.34.4460 ⚠
sm-f snRNP core complex protein, putative
— Both
LmxM.23.0650
DIM-like protein, putative, spliceosomal U5 s
— Both
LmxM.16.1250
hypothetical protein, conserved
— Both
LmxM.01.0560
pre-mRNA processing factor 3 (PRP3)/Protein o
— Both
LmxM.31.2130
RNA recognition motif. (a.k.a. RRM, RBD, or R
— Both
LmxM.28.2740a ⚠
hypothetical protein
— OG7
LmxM.36.4360
Regulatory particle triple-A ATPase subunit 6
— OG6
LmxM.16.1630
Putative snoRNA binding domain containing pro
— Both
LmxM.31.2200 ⚠
U5 small nuclear ribonucleoprotein component,
— Both
LmxM.36.6030
hypothetical protein, conserved
— Both
LmxM.36.0990 ⚠
40S ribosomal protein S10, putative
— Both
LmxM.36.0980 ⚠
40S ribosomal protein S10, putative
— Both
LmxM.27.1460
proteasome regulatory non-ATP-ase subunit 3,
— Both
LmxM.26.0005 ⚠
Lsm7p protein, putative
— OG7
LmxM.01.0160 ⚠
LSM domain containing protein, putative
— OG7
LmxM.13.1090
proteasome regulatory ATPase subunit 2, putat
— OG6
LmxM.28.2750partial ⚠
hypothetical protein
— OG7
LmxM.28.2740 ⚠
activated protein kinase c receptor (LACK)
— OG7
LmxM.36.0580 ⚠
hypothetical protein, unknown function
— OG7
LmxM.29.1400 ⚠
WD domain, G-beta repeat, putative
— OG7
LmxM.33.4620 ⚠
cyclic nucleotide-binding domain containing p
— OG7
LmxM.36.0535 ⚠
small nuclear ribonucleaoprotein, putative
— OG7
LmxM.31.0715 ⚠
U6 snRNA-associated Sm-like protein LSm4p
— OG7
LmxM.01.0640 ⚠
HSP70-like protein
— OG7
LmxM.18.1370 ⚠
heat shock protein, putative
— OG7
LmxM.26.0900 ⚠
chaperone protein-like protein, heat shock 70
— OG7
LmxM.34.4710 ⚠
Hsp70 protein, putative
— OG7
LmxM.36.0180 ⚠
elongation factor 2
— OG7
LmxM.25.2080 ⚠
elongation factor 2-like protein
— OG7
LmxM.21.0760
proteasome regulatory non-ATP-ase subunit 5,
— Both
LmxM.28.2820 ⚠
heat shock protein 70, putative
— OG6
LmxM.28.1200 ⚠
luminal binding protein 1 (BiP), putative
— Both
LmxM.12.0210
proteasome regulatory ATPase subunittcc1l8.3,
— OG6
LmxM.31.0390
19S proteasome non-atpase subunit 8
— Both
LmxM.08_29.0120
proteasome regulatory non-ATPase subunit, put
— Both
LmxM.15.1190 ⚠
cyclic nucleotide-binding domain containing p
— Both
LmxM.17.0800
OSM3-like kinesin, putative
— OG6
LmxM.32.0280
hypothetical protein, conserved
— Both
LmxM.28.2770 ⚠
heat-shock protein hsp70, putative
— Both
LmxM.19.1120
proteasome regulatory non-ATP-ase subunit 9,
— Both
LmxM.15.1200
protein kinase, putative
— OG6
LmxM.07.1120
proteasome regulatory non-ATP-ase subunit, pu
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.