LmxM.03.0270

FYVE zinc finger/Apolipoprotein A1/A4/E domain containing protein, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_163591 OG7: OG7_0019980 109 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 109 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.21.1020 ⚠
dynein arm light chain, putative
— OG7
LmxM.21.1330partial ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LmxM.05.0400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LmxM.32.1180 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LmxM.25.0170 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmxM.16.1550 ⚠
Component of motile flagella 6, putative
— OG7
LmxM.11.0420 ⚠
regulator of chromatin condensation, putative
— OG7
LmxM.25.0610 ⚠
Regulatory-associated protein of TOR1
— OG7
LmxM.24.0930 ⚠
hypothetical protein, conserved
— OG7
LmxM.26.1120 ⚠
axonemal dynein light chain, putative
— OG7
LmxM.26.1950 ⚠
microtubule-associated protein, putative
— OG7
LmxM.36.3070 ⚠
fibrillarin
— OG7
LmxM.33.3430 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmxM.18.0460 ⚠
tubulin-specific chaperone, putative
— OG7
LmxM.18.1100 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmxM.08_29.1100 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmxM.20.0260 ⚠
Midasin, putative
— OG7
LmxM.27.2170 ⚠
hypothetical protein, conserved
— OG7
LmxM.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmxM.26.0740 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmxM.17.0240 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmxM.19.0100 ⚠
fibrillarin, putative
— OG7
LmxM.13.0270 ⚠
hypothetical protein, conserved
— OG7
LmxM.24.0840 ⚠
dynein light chain p28, axonemal, putative
— OG7
LmxM.28.1760 ⚠
protein kinase, putative
— OG7
LmxM.24.1970 ⚠
Nucleoporin NUP76
— OG7
LmxM.04.0520 ⚠
huntingtin interacting protein (HIP), putativ
— OG7
LmxM.24.1960 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.2720 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmxM.04.0550 ⚠
Intraflagellar transport protein 139, putativ
— OG7
LmxM.11.0830 ⚠
hypothetical protein, conserved
— OG7
LmxM.17.1150 ⚠
5'-3' exoribonuclease B, putative
— OG7
LmxM.06.0260 ⚠
5'-3' exoribonuclease A, putative
— OG7
LmxM.36.1790 ⚠
5'-3' exoribonuclease D, putative
— OG7
LmxM.34.2670 ⚠
ankyrin repeat protein, putative
— OG7
LmxM.14.0100 ⚠
hypothetical protein, conserved
— OG7
LmxM.19.1010 ⚠
WD domain, G-beta repeat, putative
— OG7
LmxM.33.2820 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LmxM.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LmxM.29.1990 ⚠
cyclosome subunit-like protein
— OG7
LmxM.30.3110 ⚠
Flagellum attachment zone protein 14
— OG7
LmxM.21.0530 ⚠
hypothetical protein, conserved
— OG7
LmxM.19.0940 ⚠
CAP-Gly domain containing protein, putative
— OG7
LmxM.13.0160 ⚠
protein kinase A regulatory subunit
— OG7
LmxM.09.0990 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LmxM.31.1340 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmxM.36.4060 ⚠
regulator of chromosome condensation 1-like p
— OG7
LmxM.31.1470 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LmxM.15.1200 ⚠
protein kinase, putative
— OG7
LmxM.36.6340 ⚠
HECT E3 ligase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.