LmxM.04.0520

huntingtin interacting protein (HIP), putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_150890 OG7: OG7_0000441 105 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 105 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.36.6350 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmxM.25.0170 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmxM.16.1550 ⚠
Component of motile flagella 6, putative
— OG7
LmxM.18.0190 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG7
LmxM.25.0610 ⚠
Regulatory-associated protein of TOR1
— OG7
LmxM.24.0930 ⚠
hypothetical protein, conserved
— OG7
LmxM.25.0520 ⚠
RNA-binding protein, putative
— OG7
LmxM.33.3430 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmxM.20.0260 ⚠
Midasin, putative
— OG7
LmxM.27.2170 ⚠
hypothetical protein, conserved
— OG7
LmxM.08_29.1340 ⚠
RNA-binding protein, putative
— OG7
LmxM.28.1760 ⚠
protein kinase, putative
— OG7
LmxM.24.1970 ⚠
Nucleoporin NUP76
— OG7
LmxM.24.1960 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.1340 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmxM.08_29.1350 ⚠
RNA binding protein, putative
— OG7
LmxM.31.3930 ⚠
HECT E3 ligase, putative
— OG7
LmxM.36.2630 ⚠
protein kinase, putative
— OG7
LmxM.30.3110 ⚠
Flagellum attachment zone protein 14
— OG7
LmxM.29.1990 ⚠
cyclosome subunit-like protein
— OG7
LmxM.11.0950 ⚠
hypothetical protein, conserved
— OG7
LmxM.11.0390 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.2300 ⚠
hypothetical protein, conserved
— OG7
LmxM.06.0460 ⚠
ATP-NAD kinase-like protein
— OG7
LmxM.01.0600 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LmxM.07.0100 ⚠
pitrilysin-like metalloprotease, metallo-pept
— OG7
LmxM.34.5310 ⚠
GTP-binding protein, putative
— OG7
LmxM.33.3550 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LmxM.04.0550 ⚠
Intraflagellar transport protein 139, putativ
— OG7
LmxM.24.1490 ⚠
WD domain, G-beta repeat, putative
— OG7
LmxM.13.0550 ⚠
Uncharacterized ACR, COG1678, putative
— OG7
LmxM.31.3970 ⚠
cAMP response protein 1, putative
— OG7
LmxM.33.2820 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LmxM.15.1200 ⚠
protein kinase, putative
— OG7
LmxM.13.0160 ⚠
protein kinase A regulatory subunit
— OG7
LmxM.31.1790 ⚠
hypothetical protein, conserved
— OG7
LmxM.12.0110 ⚠
hypothetical protein, conserved
— OG7
LmxM.03.0270 ⚠
FYVE zinc finger/Apolipoprotein A1/A4/E domai
— OG7
LmxM.26.0580 ⚠
Protein of unknown function (DUF525), putativ
— OG7
LmxM.33.1415 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— OG7
LmxM.36.1400 ⚠
The ARF-like 2 binding protein BART, putative
— OG7
LmxM.34.2340 ⚠
ribonuclease, putative
— OG7
LmxM.21.0950 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LmxM.33.1410 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— OG7
LmxM.23.1630 ⚠
hypothetical protein, conserved
— OG7
LmxM.04.1190 ⚠
tRNA nucleotidyltransferase, putative
— OG7
LmxM.36.2250 ⚠
developmentally regulated GTP-binding protein
— OG7
LmxM.25.1730 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.3070 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.1400 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.