LmxM.22.0650

guide RNA associated protein, GAP2, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_139815 OG7: OG7_0037740 144 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 144 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.18.0550
hypothetical protein, conserved
— Both
LmxM.32.1910
ribosome assembly protein RRB1, putative
— Both
LmxM.18.1220 ⚠
prolyl-tRNA synthetase, putative,bifunctional
— Both
LmxM.18.1210 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LmxM.18.1320
hypothetical protein, conserved
— Both
LmxM.29.0460 ⚠
aspartyl-tRNA synthetase, putative
— Both
LmxM.36.1955 ⚠
TLD, putative
— OG7
LmxM.13.0940
N(2), N(2)-dimethylguanosine tRNA methyltrans
— Both
LmxM.34.1190 ⚠
NADH-dependent fumarate reductase, putative
— Both
LmxM.07.0800 ⚠
flavoprotein subunit-like protein
— Both
LmxM.29.1230
Zinc finger, C3HC4 type (RING finger), putati
— Both
LmxM.04.0450 ⚠
calpain-like cysteine peptidase, putative
— OG6
LmxM.18.0070 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— Both
LmxM.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— Both
LmxM.34.2940 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
LmxM.28.2770 ⚠
heat-shock protein hsp70, putative
— OG6
LmxM.26.1240 ⚠
heat shock protein 70-related protein
— OG6
LmxM.28.2780 ⚠
heat-shock protein hsp70, putative
— OG6
LmxM.36.4230
paraflagellar rod component, putative
— OG6
LmxM.07.0760 ⚠
6-phosphofructo-2-kinase-like protein
— Both
LmxM.25.2210
hypothetical protein, conserved
— Both
LmxM.29.3260 ⚠
Ankyrin repeats (3 copies), putative
— OG6
LmxM.36.3100
ATP synthase, putative
— Both
LmxM.08_29.0020
transcription factor-like protein
— Both
LmxM.28.0680 ⚠
Ankyrin repeats (3 copies), putative
— OG6
LmxM.20.1185 ⚠
calpain-like cysteine peptidase, putative
— OG6
LmxM.21.1650 ⚠
protein kinase, putative
— Both
LmxM.01.0610
DNA-damage inducible protein DDI1-like protei
— Both
LmxM.26.0860 ⚠
RNA-editing complex protein MP100, putative
— OG7
LmxM.20.0950 ⚠
conserved protein, unknown function
— OG7
LmxM.08_29.2180 ⚠
Domain of unknown function (DUF4379), putativ
— OG7
LmxM.01.0710 ⚠
ubiquitin activating enzyme, putative
— OG7
LmxM.26.0310 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LmxM.36.0150 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LmxM.14.1070 ⚠
protein kinase, putative
— OG7
LmxM.36.0490 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LmxM.08_29.0290 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LmxM.05.0850 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LmxM.26.0420 ⚠
pseudouridylate synthase-like protein
— OG7
LmxM.34.2450 ⚠
HECT E3 ligase, putative
— OG7
LmxM.17.0540 ⚠
ATPase family associated with various cellula
— OG7
LmxM.33.4030 ⚠
geranylgeranyltransferase, putative
— OG7
LmxM.29.1090 ⚠
WW domain containing protein, putative
— OG7
LmxM.20.1090 ⚠
hypothetical protein, conserved
— OG7
LmxM.34.3250 ⚠
replication factor C, subunit 3, putative
— OG7
LmxM.25.1705 ⚠
LSM domain containing protein, putative
— OG7
LmxM.01.0160 ⚠
LSM domain containing protein, putative
— OG7
LmxM.36.6710 ⚠
replication factor C subunit 3, putative
— OG7
LmxM.06.0940 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.1420 ⚠
Zn-finger in Ran binding protein and others,
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.