LmxM.18.0090

alpha glucosidase II subunit, putative

Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_100592 OG7: OG7_0001836 118 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 118 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LmxM.24.0110 ⚠ poly A polymerase regulatory subunit, putativ	—	OG7 TCSYLVIO_005809 ↔ TCSYLVIO_006141	OG7
LmxM.28.1580 ⚠ phosphonopyruvate decarboxylase-like protein	—	OG6 TCSYLVIO_002596 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_002596 ↔ TCSYLVIO_006141	Both
LmxM.29.3440 ⚠ DNA ligase I, putative	—	OG6 TCSYLVIO_003375 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_003375 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_006141	Both
LmxM.34.0390 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_005084 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_005084 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_005084 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_005084 ↔ TCSYLVIO_006141	Both
LmxM.29.3300 ⚠ UV excision repair RAD23-like protein	—	OG6 TCSYLVIO_003361 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_003361 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_003361 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_003361 ↔ TCSYLVIO_006141	Both
LmxM.08_29.2110 ⚠ UDP-glucose:glycoprotein glucosyltransferase,	—	OG6 TCSYLVIO_004363 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_004363 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_006141	Both
LmxM.18.0010 ⚠ kinetoplast polyadenylation/uridylation facto	—	OG6 TCSYLVIO_000834 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_000834 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_006141	Both
LmxM.22.1240 ⚠ translation initiation factor IF-2, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_001768 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_006141	Both
LmxM.05.0820 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_001973 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_006141	Both
LmxM.36.5620 ⚠ isoleucyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006141	Both
LmxM.36.2170 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_004998 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_006141	Both
LmxM.08_29.2540 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_004998 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_006141	Both
LmxM.23.1470 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_000215 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_000215 ↔ TCSYLVIO_006141	Both
LmxM.34.3380 ⚠ poly A polymerase regulatory subunit, putativ	—	OG6 TCSYLVIO_005809 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_005809 ↔ TCSYLVIO_006141	Both
LmxM.19.0800 ⚠ ABC transporter, putative	—	OG6 TCSYLVIO_006012 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_006012 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_006012 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_006012 ↔ TCSYLVIO_006141	Both
LmxM.36.0070 ⚠ stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_003496 ↔ TCSYLVIO_006141	OG6
LmxM.27.2390 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_003496 ↔ TCSYLVIO_006141	OG6
LmxM.25.0170 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_005414 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_005414 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_005414 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_005414 ↔ TCSYLVIO_006141	Both
LmxM.22.1540 ⚠ alanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_001889 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_006141	Both
LmxM.28.0450 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_002525 ↔ TCSYLVIO_006141 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_006141 +4 more	Both
LmxM.05.0270 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_004813 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_004813 ↔ TCSYLVIO_006141	Both
LmxM.31.3980 ⚠ Gar1/Naf1 RNA binding region, putative	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_000836 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_006141	Both
LmxM.11.0210 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_006141	Both
LmxM.03.0910 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_006141	Both
LmxM.04.0330 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_006141	OG7
LmxM.28.0330 ⚠ rrp44p homologue, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_006141	OG7
LmxM.33.3430 ⚠ cleavage and polyadenylation specificity fact	—	OG7 TCSYLVIO_005414 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_005414 ↔ TCSYLVIO_006141	OG7
LmxM.32.0310 ⚠ ATP-binding cassette sub-family F member 1, p	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_006012 ↔ TCSYLVIO_006141	OG7
LmxM.03.0160 ⚠ ABC transporter protein, putative	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_006012 ↔ TCSYLVIO_006141	OG7
LmxM.36.6080 ⚠ rab-like GTPase activating protein, putative	—	OG7 TCSYLVIO_004663 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_004663 ↔ TCSYLVIO_006141	OG7
LmxM.31.0100 ⚠ NLI interacting factor-like phosphatase, puta	—	OG7 TCSYLVIO_006141 ↔ TCSYLVIO_007685	OG7
LmxM.24.1340 ⚠ translation initiation factor IF-2, putative	—	OG7 TCSYLVIO_001768 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_006141	OG7
LmxM.30.0930 ⚠ sodium stibogluconate resistance protein, put	—	OG7 TCSYLVIO_001846 ↔ TCSYLVIO_006141	OG7
LmxM.30.0960 ⚠ hypothetical protein	—	OG7 TCSYLVIO_001846 ↔ TCSYLVIO_006141	OG7
LmxM.30.0950 ⚠ hypothetical protein	—	OG7 TCSYLVIO_001846 ↔ TCSYLVIO_006141	OG7
LmxM.17.1130 ⚠ NOL1/NOP2/sun family, putative	—	OG7 TCSYLVIO_004998 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_006141	OG7
LmxM.18.1110 ⚠ Multisite-specific tRNA:(cytosine-C(5))-methy	—	OG7 TCSYLVIO_004998 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_006141	OG7
LmxM.34.2950 ⚠ pentatricopeptide repeat domain containing pr	—	OG7 TCSYLVIO_000834 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_006141	OG7
LmxM.33.1140 ⚠ dihydrouridine synthase (Dus), putative	—	OG7 TCSYLVIO_006140 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_006141 ↔ TCSYLVIO_009102	OG7
LmxM.21.0030 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_006140 ↔ TCSYLVIO_006877 OG7 TCSYLVIO_006141 ↔ TCSYLVIO_006877	OG7
LmxM.34.2620 ⚠ TFIIF-stimulated CTD phosphatase, putative	—	OG7 TCSYLVIO_006141 ↔ TCSYLVIO_007685	OG7
LmxM.30.1930 ⚠ dihydrouridine synthase (Dus), putative	—	OG7 TCSYLVIO_006140 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_006141 ↔ TCSYLVIO_009102	OG7
LmxM.08_29.2400 ⚠ NLI interacting factor-like phosphatase, puta	—	OG7 TCSYLVIO_006141 ↔ TCSYLVIO_007685	OG7
LmxM.16.1130 ⚠ tyrosyl or methionyl-tRNA synthetase-like pro	—	OG7 TCSYLVIO_006141 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_006140 ↔ TCSYLVIO_010624	OG7
LmxM.21.0040 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_006140 ↔ TCSYLVIO_006877 OG7 TCSYLVIO_006141 ↔ TCSYLVIO_006877	OG7
LmxM.36.4100 ⚠ glycosyl hydrolase-like protein	—	OG7 TCSYLVIO_006140 ↔ TCSYLVIO_006141	OG7
LmxM.36.0470 ⚠ dihydrouridine synthase domain protein-like p	—	OG7 TCSYLVIO_006140 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_006141 ↔ TCSYLVIO_009102	OG7
LmxM.36.6780 ⚠ nuclear lim interactor-interacting factor, pu	—	OG7 TCSYLVIO_006141 ↔ TCSYLVIO_007685	OG7
LmxM.23.0300 ⚠ tryptophanyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_006141 ↔ TCSYLVIO_010724 OG7 TCSYLVIO_006140 ↔ TCSYLVIO_010724	OG7
LmxM.25.2030 ⚠ dullard-like phosphatase domain containing pr	—	OG7 TCSYLVIO_006141 ↔ TCSYLVIO_007685	OG7

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