LmxM.03.0910

inorganic pyrophosphatase, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_100346 OG7: OG7_0003350 286 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 286 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.01.0710 ⚠
ubiquitin activating enzyme, putative
— OG7
LmxM.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.29.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.34.0020 ⚠
pyruvate kinase
— Both
LmxM.23.0110 ⚠
mannose-1-phosphate guanyltransferase
— Both
LmxM.34.0030 ⚠
pyruvate kinase, putative
— Both
LmxM.20.1180 ⚠
calpain-like cysteine peptidase
— OG6
LmxM.33.2340 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LmxM.08.0220 ⚠
ubiquitin-activating enzyme-like protein
— Both
LmxM.04.0450 ⚠
calpain-like cysteine peptidase, putative
— OG6
LmxM.20.1185 ⚠
calpain-like cysteine peptidase, putative
— OG6
LmxM.36.4230 ⚠
paraflagellar rod component, putative
— OG6
LmxM.27.2410 ⚠
aldo-keto reductase-like protein
— OG7
LmxM.08.0870 ⚠
hypothetical protein, unknown function
— OG7
LmxM.31.3750 ⚠
Methyltransferase TYW3, putative
— OG7
LmxM.13.0130 ⚠
Kinesin-13 2
— OG7
LmxM.01.0030 ⚠
Kinesin-13 1, putative
— OG7
LmxM.30.0290 ⚠
Kinesin-13 4, putative
— OG7
LmxM.13.1610 ⚠
Kinesin-13 5, putative
— OG7
LmxM.32.2570 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmxM.05.0820 ⚠
hypothetical protein, conserved
— Both
LmxM.01.0610 ⚠
DNA-damage inducible protein DDI1-like protei
— Both
LmxM.21.0810 ⚠
methionyl-tRNA synthetase, putative
— Both
LmxM.16.0580 ⚠
dihydroorotase, putative
— Both
LmxM.14.1190 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— Both
LmxM.26.0310 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
LmxM.29.2320 ⚠
SET domain containing protein, putative
— Both
LmxM.27.0380 ⚠
Nuclear pore complex protein 158
— Both
LmxM.20.1710 ⚠
tRNA (Uracil-5-)-methyltransferase, putative
— Both
LmxM.08_29.0020 ⚠
transcription factor-like protein
— Both
LmxM.25.0170 ⚠
cleavage and polyadenylation specificity fact
— Both
LmxM.25.2020 ⚠
hypothetical protein, conserved
— Both
LmxM.32.0316 ⚠
heat shock protein 83-1
— +2 more Both
LmxM.26.1900 ⚠
hypothetical protein, conserved
— Both
LmxM.29.1120 ⚠
importin alpha, putative
— Both
LmxM.31.0870 ⚠
phenylalanyl-tRNA synthetase alpha chain, put
— Both
LmxM.36.5620 ⚠
isoleucyl-tRNA synthetase, putative
— Both
LmxM.20.0250 ⚠
deoxyhypusine synthase, putative
— Both
LmxM.29.0610 ⚠
nitrate reductase, putative
— OG6
LmxM.30.2600 ⚠
calreticulin, putative
— Both
LmxM.34.1050 ⚠
protein kinase, putative
— OG6
LmxM.31.3680 ⚠
enoyl-CoA hydratase/isomerase family protein,
— Both
LmxM.21.0640 ⚠
phosphoglucomutase, putative
— Both
LmxM.03.0760 ⚠
hypothetical protein, conserved
— Both
LmxM.19.0800 ⚠
ABC transporter, putative
— Both
LmxM.08_29.1580 ⚠
XPC-binding domain containing protein, putati
— Both
LmxM.29.0630 ⚠
histidyl-tRNA synthetase, putative
— Both
LmxM.31.0080 ⚠
N-myristoyl transferase, putative
— Both
LmxM.36.3580 ⚠
Protein of unknown function (DUF2009), putati
— Both
LmxM.28.0450 ⚠
DIS3-like exonuclease, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.