LmxM.23.0110

mannose-1-phosphate guanyltransferase

Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_100460 OG7: OG7_0001668 182 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 182 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LmxM.06.0370 glutamine synthetase, putative	—	OG6 Tb927.7.4970 ↔ Tb927.8.2050 OG6 TCSYLVIO_001811 ↔ TCSYLVIO_007603 OG7 Tb927.7.4970 ↔ Tb927.8.2050 OG7 TCSYLVIO_001811 ↔ TCSYLVIO_007603	Both
LmxM.14.1360 myo-inositol-1-phosphate synthase	—	OG6 TCSYLVIO_007453 ↔ TCSYLVIO_007603 OG6 Tb927.10.7110 ↔ Tb927.8.2050 OG7 Tb927.10.7110 ↔ Tb927.8.2050 OG7 TCSYLVIO_007453 ↔ TCSYLVIO_007603	Both
LmxM.03.0910 ⚠ inorganic pyrophosphatase, putative	—	OG6 Tb927.11.7080 ↔ Tb927.8.2050 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007603 OG7 Tb927.11.7080 ↔ Tb927.8.2050 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007603	Both
LmxM.11.0210 ⚠ acidocalcisomal pyrophosphatase	—	OG6 Tb927.11.7080 ↔ Tb927.8.2050 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007603 OG7 Tb927.11.7080 ↔ Tb927.8.2050 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007603	Both
LmxM.14.1370 ⚠ tyrosyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010624	Both
LmxM.11.0990 ⚠ adaptin-related protein-like protein	—	OG7 TCSYLVIO_004597 ↔ TCSYLVIO_007603	OG7
LmxM.25.2410 hypothetical protein, conserved	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010323 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010323	Both
LmxM.36.0130 PUB domain containing protein, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009932 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009932	Both
LmxM.08.0220 ⚠ ubiquitin-activating enzyme-like protein	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010542 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010542	Both
LmxM.33.1990 Zeta toxin, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010958 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010958	Both
LmxM.10.0270 exonuclease, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010944 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010944	Both
LmxM.28.2370 ⚠ serine hydroxymethyltransferase	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010621 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010621	Both
LmxM.14.0450 ⚠ N-terminal conserved domain of Nudc./CS domai	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010327 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010327	Both
LmxM.23.0270 pteridine reductase 1	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008848 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008848	Both
LmxM.08.0890 ⚠ mitochondrial DNA polymerase beta	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010588 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010588	Both
LmxM.08_29.0060 ⚠ tryptophanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010724 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010724	Both
LmxM.32.0314 ⚠ heat shock protein 83-1	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008621 +2 more	Both
LmxM.21.1770 ATP synthase F1 subunit gamma protein, putati	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009375 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009375	Both
LmxM.36.3090 hypothetical protein, conserved	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009198 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009198	Both
LmxM.14.1320 ⚠ serine hydroxymethyltransferase, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010621 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010621	Both
LmxM.08.0410 WD domain, G-beta repeat, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010560	Both
LmxM.17.0350 ⚠ dihydrouridine synthase (Dus), putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009102	Both
LmxM.05.0180 dihydrolipoamide branched chain transacylase,	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009880 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009880	Both
LmxM.32.0312 ⚠ heat shock protein 83-1	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008621 +2 more	Both
LmxM.32.0316 ⚠ heat shock protein 83-1	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008621 +2 more	Both
LmxM.08_29.0020 transcription factor-like protein	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010728 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010728	Both
LmxM.20.1710 tRNA (Uracil-5-)-methyltransferase, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008409 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008409	Both
LmxM.21.0810 methionyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_007991	Both
LmxM.29.0560 hypothetical protein, conserved	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_007603	Both
LmxM.24.2020 tubulin folding cofactor D, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_007603	Both
LmxM.30.2270 hypothetical protein, conserved	—	OG6 TCSYLVIO_003958 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_003958 ↔ TCSYLVIO_007603	Both
LmxM.19.0800 ⚠ ABC transporter, putative	—	OG6 TCSYLVIO_006012 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007603	Both
LmxM.36.0070 ⚠ stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007603	OG6
LmxM.27.2390 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007603	OG6
LmxM.25.0170 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_005414 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_005414 ↔ TCSYLVIO_007603	Both
LmxM.22.1540 alanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_007603	Both
LmxM.28.0450 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_007603 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007603	Both
LmxM.36.6350 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG6 TCSYLVIO_000055 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_007603	Both
LmxM.23.1630 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_000055 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_007603	Both
LmxM.31.3980 Gar1/Naf1 RNA binding region, putative	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_007603	Both
LmxM.26.1900 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003586 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_003586 ↔ TCSYLVIO_007603	Both
LmxM.10.1200 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003586 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_003586 ↔ TCSYLVIO_007603	Both
LmxM.25.2300 Leucine Rich repeats (2 copies), putative	—	OG6 TCSYLVIO_006421 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_006421 ↔ TCSYLVIO_007603	Both
LmxM.36.4230 paraflagellar rod component, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_007603	OG6
LmxM.34.0700 vacuolar ATP synthase subunit d, putative	—	OG6 TCSYLVIO_005104 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_005104 ↔ TCSYLVIO_007603	Both
LmxM.32.2570 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_007603	OG7
LmxM.04.0330 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007603	OG7
LmxM.28.0330 ⚠ rrp44p homologue, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007603	OG7
LmxM.23.0300 ⚠ tryptophanyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010724	OG7
LmxM.21.0040 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_006877 ↔ TCSYLVIO_007603	OG7

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