LmxM.14.1360

myo-inositol-1-phosphate synthase

Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_100830 OG7: OG7_0006574 184 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 184 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LmxM.04.0330 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_280470.1	OG7
LmxM.11.1000 pyruvate phosphate dikinase, putative	—	OG6 LdBPK_111000.1 ↔ LdBPK_141450.1 OG6 Tb927.10.7110 ↔ Tb927.11.6280 OG7 Tb927.10.7110 ↔ Tb927.11.6280 OG7 LdBPK_111000.1 ↔ LdBPK_141450.1	Both
LmxM.23.0110 mannose-1-phosphate guanyltransferase	—	OG6 TCSYLVIO_007453 ↔ TCSYLVIO_007603 OG6 Tb927.10.7110 ↔ Tb927.8.2050 OG7 Tb927.10.7110 ↔ Tb927.8.2050 OG7 TCSYLVIO_007453 ↔ TCSYLVIO_007603	Both
LmxM.28.0450 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_007453 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007453 +1 more	Both
LmxM.32.0310 ⚠ ATP-binding cassette sub-family F member 1, p	—	OG6 LdBPK_141450.1 ↔ LdBPK_330340.1 OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_330340.1	Both
LmxM.03.0160 ⚠ ABC transporter protein, putative	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_330340.1	OG7
LmxM.32.1400 ⚠ protein kinase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_331490.1 OG7 LdBPK_141450.1 ↔ LdBPK_331490.1 OG7 TCSYLVIO_007401 ↔ TCSYLVIO_007453	Both
LmxM.19.0800 ⚠ ABC transporter, putative	—	OG6 TCSYLVIO_006012 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_330340.1	Both
LmxM.28.0330 ⚠ rrp44p homologue, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_280470.1 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_280470.1	Both
LmxM.25.0870 ⚠ protein kinase, putative	—	OG6 TCSYLVIO_007401 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_331490.1 OG7 TCSYLVIO_007401 ↔ TCSYLVIO_007453	Both
LmxM.34.4550 hypothetical protein, conserved	—	OG6 TCSYLVIO_005710 ↔ TCSYLVIO_007453 OG6 LdBPK_141450.1 ↔ LdBPK_354620.1 OG7 LdBPK_141450.1 ↔ LdBPK_354620.1 OG7 TCSYLVIO_005710 ↔ TCSYLVIO_007453	Both
LmxM.26.0470 hypothetical protein, conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_260460.1 OG7 LdBPK_141450.1 ↔ LdBPK_260460.1	Both
LmxM.03.0910 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007453	Both
LmxM.11.0210 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007453	Both
LmxM.31.3980 Gar1/Naf1 RNA binding region, putative	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_007453	Both
LmxM.22.1540 alanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_007453	Both
LmxM.25.0170 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_005414 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_005414 ↔ TCSYLVIO_007453	Both
LmxM.27.2390 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007453	OG6
LmxM.36.0070 ⚠ stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007453	OG6
LmxM.12.0280 ornithine decarboxylase, putative	—	OG6 LdBPK_120105.1 ↔ LdBPK_141450.1 OG7 LdBPK_120105.1 ↔ LdBPK_141450.1	Both
LmxM.08_29.2540 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007453	Both
LmxM.36.2170 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007453	Both
LmxM.36.5620 isoleucyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_007453	Both
LmxM.05.0820 hypothetical protein, conserved	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_007453	Both
LmxM.22.1240 ⚠ translation initiation factor IF-2, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007453	Both
LmxM.16.0310 ⚠ Met-10+ like-protein, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_160320.1 OG7 LdBPK_141450.1 ↔ LdBPK_160320.1	Both
LmxM.02.0710 ⚠ serine peptidase, putative, ATP-dependent Clp	—	OG6 LdBPK_141450.1 ↔ LdBPK_291360.1 OG7 LdBPK_141450.1 ↔ LdBPK_291360.1	Both
LmxM.08_29.1270 ⚠ ATP-dependent Clp protease subunit, heat shoc	—	OG6 LdBPK_141450.1 ↔ LdBPK_291360.1 OG7 LdBPK_141450.1 ↔ LdBPK_291360.1	Both
LmxM.29.2040 cysteine peptidase, Clan CA, family C2, putat	—	OG6 LdBPK_141450.1 ↔ LdBPK_302040.1	OG6
LmxM.26.1160 ⚠ RNA pseudouridylate synthase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_261140.1 OG7 LdBPK_141450.1 ↔ LdBPK_261140.1	Both
LmxM.24.1890 ⚠ cyclin 10	—	OG6 LdBPK_141450.1 ↔ LdBPK_241960.1 OG7 LdBPK_141450.1 ↔ LdBPK_241960.1	Both
LmxM.23.1010 hypothetical protein, conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_231180.1 OG7 LdBPK_141450.1 ↔ LdBPK_231180.1	Both
LmxM.33.4060 ⚠ ubiquitin hydrolase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_343890.1 OG7 LdBPK_141450.1 ↔ LdBPK_343890.1	Both
LmxM.36.6220 flagellum transition zone component, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_366480.1 OG7 LdBPK_141450.1 ↔ LdBPK_366480.1	Both
LmxM.29.0470 hypothetical protein, conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_300480.1 OG7 LdBPK_141450.1 ↔ LdBPK_300480.1	Both
LmxM.20.1550 ⚠ amidohydrolase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_201720.1 OG6 LdBPK_141450.1 ↔ LdBPK_201740.1 OG7 LdBPK_141450.1 ↔ LdBPK_201720.1 OG7 LdBPK_141450.1 ↔ LdBPK_201740.1	Both
LmxM.25.0410 translation initiation factor SUI1, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_250420.1 OG7 LdBPK_141450.1 ↔ LdBPK_250420.1	Both
LmxM.36.2830 ⚠ pre-mRNA splicing factor ATP-dependent RNA he	—	OG6 LdBPK_141450.1 ↔ LdBPK_241120.1	OG6
LmxM.29.3070 tRNA (Guanine-1)-methyltransferase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_303110.1 OG7 LdBPK_141450.1 ↔ LdBPK_303110.1	Both
LmxM.29.1380 ⚠ amidohydrolase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_201720.1 OG6 LdBPK_141450.1 ↔ LdBPK_201740.1 OG7 LdBPK_141450.1 ↔ LdBPK_201720.1 OG7 LdBPK_141450.1 ↔ LdBPK_201740.1	Both
LmxM.29.1540 phosphopantothenoylcysteine decarboxylase, pu	—	OG6 LdBPK_141450.1 ↔ LdBPK_301550.1 OG7 LdBPK_141450.1 ↔ LdBPK_301550.1	Both
LmxM.20.1570 ⚠ amidohydrolase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_201720.1 OG6 LdBPK_141450.1 ↔ LdBPK_201740.1 OG7 LdBPK_141450.1 ↔ LdBPK_201720.1 OG7 LdBPK_141450.1 ↔ LdBPK_201740.1	Both
LmxM.17.0620 ⚠ Acyl CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_141450.1	OG7
LmxM.25.0800 DNL zinc finger, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_250830.1 OG7 LdBPK_141450.1 ↔ LdBPK_250830.1	Both
LmxM.17.1310 methyltransferase domain containing protein,	—	OG6 LdBPK_141450.1 ↔ LdBPK_171410.1 OG7 LdBPK_141450.1 ↔ LdBPK_171410.1	Both
LmxM.27.1680 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_271580.1 OG7 LdBPK_141450.1 ↔ LdBPK_271580.1	Both
LmxM.15.0660 hypothetical protein, conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_150690.1 OG7 LdBPK_141450.1 ↔ LdBPK_150690.1	Both
LmxM.33.1470 EAP30/Vps36 family, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_341570.1 OG7 LdBPK_141450.1 ↔ LdBPK_341570.1	Both
LmxM.34.0750 proteasome activator protein pa26, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_350770.1 OG7 LdBPK_141450.1 ↔ LdBPK_350770.1	Both
LmxM.17.0940 Phosphorylated CTD interacting factor 1 WW do	—	OG6 LdBPK_141450.1 ↔ LdBPK_171050.1 OG7 LdBPK_141450.1 ↔ LdBPK_171050.1	Both

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