LmxM.23.0270

pteridine reductase 1
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_111087 OG7: OG7_0000101 83 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 83 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.24.2020
tubulin folding cofactor D, putative
— Both
LmxM.32.2570 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmxM.36.4230
paraflagellar rod component, putative
— OG6
LmxM.34.0700
vacuolar ATP synthase subunit d, putative
— Both
LmxM.03.0910 ⚠
inorganic pyrophosphatase, putative
— Both
LmxM.11.0210 ⚠
acidocalcisomal pyrophosphatase
— Both
LmxM.25.2300
Leucine Rich repeats (2 copies), putative
— Both
LmxM.10.1200 ⚠
hypothetical protein, conserved
— Both
LmxM.26.1900 ⚠
hypothetical protein, conserved
— Both
LmxM.23.1630 ⚠
hypothetical protein, conserved
— Both
LmxM.36.6350 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmxM.07.0760 ⚠
6-phosphofructo-2-kinase-like protein
— OG7
LmxM.29.0560
hypothetical protein, conserved
— Both
LmxM.23.0110
mannose-1-phosphate guanyltransferase
— Both
LmxM.09.0740
ubiquitin ligase, putative
— Both
LmxM.15.0281 ⚠
ribonucleoprotein p18, mitochondrial precurso
— Both
LmxM.15.0275 ⚠
ribonucleoprotein p18, mitochondrial precurso
— Both
LmxM.20.0280 ⚠
developmentally regulated phosphoprotein-like
— Both
LmxM.31.0210
Histone chaperone Rttp106-like, putative
— Both
LmxM.24.1900
WD domain, G-beta repeat/PFU (PLAA family ubi
— Both
LmxM.01.0610
DNA-damage inducible protein DDI1-like protei
— Both
LmxM.33.1220 ⚠
hypothetical protein, conserved, inositol 5-p
— OG7
LmxM.11.0990 ⚠
adaptin-related protein-like protein
— OG7
LmxM.36.5260 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
LmxM.27.1340
hypothetical protein, unknown function
— OG7
LmxM.33.3900 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LmxM.10.0160
hypothetical protein, conserved
— OG7
LmxM.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.29.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.27.1270 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmxM.34.2410 ⚠
ubiquitin hydrolase, putative,cysteine peptid
— OG7
LmxM.12.0190 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.26.0310 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
LmxM.15.1210 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
LmxM.34.4230 ⚠
hypothetical protein, conserved
— OG7
LmxM.24.0820 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LmxM.36.1150 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
LmxM.34.2340 ⚠
ribonuclease, putative
— OG7
LmxM.01.0710 ⚠
ubiquitin activating enzyme, putative
— OG7
LmxM.32.2390 ⚠
heat shock protein, putative
— OG7
LmxM.03.0800 ⚠
6-phosphofructo-2-kinase 1
— OG7
LmxM.36.0150 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LmxM.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— Both
LmxM.05.0350
trypanothione reductase
— Both
LmxM.33.2340 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LmxM.29.0350
kinesin, putative
— OG6
LmxM.19.0260
C-terminal motor kinesin, putative
— OG6
LmxM.23.1165
coronin, putative
— Both
LmxM.12.0250
cysteinyl-tRNA synthetase, putative
— Both
LmxM.34.1410
threonyl-tRNA synthetase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.