LmxM.36.5260

Adaptor protein complex AP-3 subunit beta-3
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_101595 OG7: OG7_0001921 213 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 213 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.33.4090 ⚠
GRIP domain containing protein, putative
— Both
LmxM.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmxM.05.0400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LmxM.21.1330partial ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LmxM.34.3510 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LmxM.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
LmxM.33.3900 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LmxM.20.0280 ⚠
developmentally regulated phosphoprotein-like
— OG7
LmxM.33.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LmxM.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LmxM.02.0120 ⚠
phosphatidylinositol 3-kinase-like protein
— OG7
LmxM.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmxM.31.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmxM.14.1170 ⚠
hypothetical protein, conserved
— OG7
LmxM.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmxM.26.1260 ⚠
hypothetical protein, unknown function
— OG7
LmxM.34.3500 ⚠
zinc finger protein, putative
— OG7
LmxM.18.0600 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LmxM.34.4260 ⚠
hypothetical protein, conserved
— OG7
LmxM.23.1165 ⚠
coronin, putative
— OG7
LmxM.01.0610 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
LmxM.23.1380 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LmxM.31.1400 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
LmxM.31.0870 ⚠
phenylalanyl-tRNA synthetase alpha chain, put
— OG7
LmxM.36.1360 ⚠
adenylate kinase, putative
— OG7
LmxM.16.0020 ⚠
AAA domain containing protein, putative
— OG7
LmxM.03.0910 ⚠
inorganic pyrophosphatase, putative
— OG7
LmxM.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.23.1630 ⚠
hypothetical protein, conserved
— OG7
LmxM.27.2490 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.11.0400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LmxM.20.0790 ⚠
tubulin-tyrosine ligase, putative
— OG7
LmxM.34.4930 ⚠
tubulin tyrosine ligase, putative
— OG7
LmxM.18.0370 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LmxM.08_29.0260 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LmxM.31.2930 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.29.2280 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmxM.33.4290 ⚠
nucleolar protein family a, putative
— OG7
LmxM.24.1900 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— OG7
LmxM.33.2340 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LmxM.29.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmxM.32.2780 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmxM.33.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LmxM.36.1720 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.1360 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LmxM.04.0960 ⚠
adenylate kinase, putative
— OG7
LmxM.11.0210 ⚠
acidocalcisomal pyrophosphatase
— OG7
LmxM.30.2610 ⚠
RNA polymerase ii largest subunit
— OG7
LmxM.28.2110 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmxM.36.3060 ⚠
cullin-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.