LmxM.30.2610

RNA polymerase ii largest subunit
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_100210 OG7: OG7_0001854 178 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 178 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.08.1130 ⚠
phosphoribosylpyrophosphate synthetase
— Both
LmxM.30.2970 ⚠
acetyl-CoA carboxylase
— Both
LmxM.08.0510 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
LmxM.19.0660 ⚠
DNA-directed RNA polymerases I and III subuni
— +2 more Both
LmxM.08_29.0140 ⚠
DNA-directed RNA polymerase II subunit 3, put
— +1 more Both
LmxM.20.0010 ⚠
DNA-directed RNA polymerase III, putative
— +4 more Both
LmxM.30.0160 ⚠
DNA-directed RNA polymerase II subunit 2, put
— +4 more Both
LmxM.25.0620 ⚠
RNA polymerase I second largest subunit, puta
— +1 more OG7
LmxM.36.5390 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LmxM.32.1930 ⚠
phosphoribosyl transferase, putative, phospho
— OG7
LmxM.14.1270 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LmxM.32.1110 ⚠
hypothetical protein, conserved
— OG7
LmxM.26.0600 ⚠
hypothetical protein, conserved
— OG7
LmxM.09.0250 ⚠
DNA replication licensing factor MCM4
— OG7
LmxM.36.1720 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.0250 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.16.1220 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmxM.32.2700 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
LmxM.36.2790 ⚠
Flagellar Member 1
— OG7
LmxM.23.0547 ⚠
hypothetical protein, conserved
— OG7
LmxM.24.1110 ⚠
formin-like protein
— OG7
LmxM.24.2100 ⚠
hypothetical protein, conserved
— OG7
LmxM.28.1980 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.1210 ⚠
Protein of unknown function (DUF3638)/Protein
— OG7
LmxM.34.4260 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.2440 ⚠
hypothetical protein, conserved
— OG7
LmxM.25.0940 ⚠
hypothetical protein, conserved
— OG7
LmxM.25.1490 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG7
LmxM.33.2125 ⚠
ubiquitin-like protein
— OG7
LmxM.36.0600 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LmxM.36.2010 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.2030 ⚠
ubiquitin-fusion protein
— OG7
LmxM.26.1420 ⚠
FYVE zinc finger, putative
— OG7
LmxM.16.1350 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LmxM.33.2060 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.1900 ⚠
ubiquitin-fusion protein
— OG7
LmxM.28.2385 ⚠
DNA replication licensing factor, putative
— OG7
LmxM.34.2490 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.4950 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— OG7
LmxM.18.0570 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmxM.36.5260 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
LmxM.33.1360 ⚠
Nucleoporin NUP225
— OG7
LmxM.11.0990 ⚠
adaptin-related protein-like protein
— OG7
LmxM.18.0820 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.0140 ⚠
Flagellum attachment zone protein 9
— OG7
LmxM.26.1080 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.2790 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.3060 ⚠
cullin-like protein
— OG7
LmxM.34.4910 ⚠
DNA replication factor, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.