LmxM.36.5390

phosphoribosylpyrophosphate synthetase, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_100356 OG7: OG7_0002319 171 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 171 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.30.2970 ⚠
acetyl-CoA carboxylase
— +6 more Both
LmxM.08.1130 ⚠
phosphoribosylpyrophosphate synthetase
— +6 more Both
LmxM.08.0510 ⚠
ribose-phosphate pyrophosphokinase, putative
— +5 more Both
LmxM.33.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LmxM.32.1930 ⚠
phosphoribosyl transferase, putative, phospho
— +4 more Both
LmxM.16.1350 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LmxM.30.2610 ⚠
RNA polymerase ii largest subunit
— OG7
LmxM.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmxM.21.1250 ⚠
adenylate kinase, putative
— OG7
LmxM.29.1090 ⚠
WW domain containing protein, putative
— OG7
LmxM.10.0800 ⚠
hypothetical protein, conserved
— OG7
LmxM.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LmxM.23.0120 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmxM.34.2410 ⚠
ubiquitin hydrolase, putative,cysteine peptid
— OG7
LmxM.32.2070 ⚠
mitogen-activated protein kinase, putative
— OG7
LmxM.17.0920 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmxM.33.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LmxM.26.1420 ⚠
FYVE zinc finger, putative
— OG7
LmxM.34.2490 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.1270 ⚠
hypothetical protein, conserved
— OG7
LmxM.29.0910 ⚠
HECT E3 ligase, putative
— OG7
LmxM.08.1090 ⚠
histone deacetylase, putative
— OG7
LmxM.27.1270 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmxM.36.5700 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmxM.36.5260 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
LmxM.33.2790 ⚠
hypothetical protein, conserved
— OG7
LmxM.36.3060 ⚠
cullin-like protein
— OG7
LmxM.33.2240 ⚠
Glycosyl hydrolase family 65 central catalyti
— OG7
LmxM.33.1360 ⚠
Nucleoporin NUP225
— OG7
LmxM.26.1080 ⚠
hypothetical protein, conserved
— OG7
LmxM.18.0820 ⚠
hypothetical protein, conserved
— OG7
LmxM.11.0370 ⚠
hypothetical protein, conserved
— OG7
LmxM.11.0990 ⚠
adaptin-related protein-like protein
— OG7
LmxM.32.2780 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmxM.25.0620 ⚠
RNA polymerase I second largest subunit, puta
— OG7
LmxM.29.2440 ⚠
hypothetical protein, conserved
— OG7
LmxM.12.0190 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.10.0580 ⚠
chromatin assembly factor 1 subunit A, putati
— OG7
LmxM.34.4260 ⚠
hypothetical protein, conserved
— OG7
LmxM.30.1210 ⚠
Protein of unknown function (DUF3638)/Protein
— OG7
LmxM.23.0547 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.2910 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.29.0250 ⚠
ubiquitin hydrolase, putative
— OG7
LmxM.16.1220 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmxM.36.1720 ⚠
hypothetical protein, conserved
— OG7
LmxM.08_29.0140 ⚠
DNA-directed RNA polymerase II subunit 3, put
— OG7
LmxM.05.0400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LmxM.34.3510 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LmxM.21.1330partial ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.